Results 191 to 200 of about 154,769 (339)

NF‐κB Is a Potential Therapeutic Target for Histone Deacetylase Inhibitor‐Resistant Cutaneous T‐Cell Lymphoma

open access: yesCancer Science, Volume 117, Issue 2, Page 407-417, February 2026.
We identified a novel mechanism of resistance to histone deacetylase inhibitors (HDACi) in cutaneous T‐cell lymphoma (CTCL), mediated by NF‐κB activation. This finding highlights NF‐κB as a potential therapeutic target for overcoming HDACi resistance in CTCL.
Yuto Takahashi   +10 more
wiley   +1 more source

Current development of CBP/p300 inhibitors in the last decade

open access: green, 2020
Zhangxu He   +5 more
openalex   +1 more source

[A TrAdaBoost-based method for detecting multiple subjects' P300 potentials]. [PDF]

open access: green, 2019
Guizhi Xu   +4 more
openalex   +1 more source

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

open access: yesCell Proliferation, Volume 59, Issue 2, February 2026.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie   +10 more
wiley   +1 more source

Figure 6 from p300 KAT Regulates SOX10 Stability and Function in Human Melanoma

open access: gold
Aaron Waddell   +8 more
openalex   +1 more source

Raccoons vs Demons: multiclass labeled P300 dataset [PDF]

open access: green, 2020
Vladislav Goncharenko   +2 more
openalex   +1 more source

MSC‐Derived Secretome and Exosomes in Dermatology: Mechanisms, Therapeutic Opportunities, and Scientific Challenges—A Narrative Review

open access: yesInternational Journal of Dermatology, Volume 65, Issue 2, Page 257-272, February 2026.
ABSTRACT Mesenchymal stromal cells (MSCs) exert their effects primarily through paracrine signaling via soluble factors and extracellular vesicles (EVs), especially exosomes. These acellular components offer regenerative and immunomodulatory benefits with fewer safety and logistical constraints than cell‐based therapies.
Marcela da Costa Pereira Cestari   +2 more
wiley   +1 more source

Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation [PDF]

open access: gold, 2018
Ryan Raisner   +13 more
openalex   +1 more source

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