Results 41 to 50 of about 154,769 (339)

p300/CBP and cancer [PDF]

Oncogene, 2004
p300 and cyclic AMP response element-binding protein (CBP) are adenoviral E1A-binding proteins involved in multiple cellular processes, and function as transcriptional co-factors and histone acetyltransferases. Germline mutation of CBP results in Rubinstein-Taybi syndrome, which is characterized by an increased predisposition to childhood malignancies.
Narayanan Gopalakrishna, Iyer, Hilal, Ozdag, Carlos, Caldas   +2 more
openaire   +2 more sources

Comparison of an open-hardware electroencephalography amplifier with medical grade device in brain-computer interface applications [PDF]

, 2016
Brain-computer interfaces (BCI) are promising communication devices between humans and machines. BCI based on non-invasive neuroimaging techniques such as electroencephalography (EEG) have many applications , however the dissemination of the technology ...
Frey, Jérémy
core   +3 more sources

A comparison of cognitive functions in non-hypoxemic chronic obstructive pulmonary disease (COPD) patients and age-matched healthy volunteers using mini-mental state examination questionnaire and event-related potential, P300 analysis

Lung India, 2013
Objective: To assess sub-clinical cognitive dysfunctions in stable chronic obstructive pulmonary disease (COPD) patients having no hypoxemia vs. age-matched healthy volunteers using (i) an electrophysiological test: Auditory event related potential, P300
Prem Parkash Gupta, Sushma Sood, Atulya Atreja, Dipti Agarwal   +3 more
doaj   +1 more source

Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer. [PDF]

, 2018
BACKGROUND:Although canonical Wnt signaling is known to promote tumorigenesis in pancreatic ductal adenocarcinoma (PDAC), a cancer driven principally by mutant K-Ras, the detailed molecular mechanisms by which the Wnt effector β-catenin regulates such ...
Chen, Yibu, Genyk, Yuri S, Kahn, Michael, Lai, Keane KY, Lenz, Heinz-Josef, Lin, David P, Manegold, Philipp, Nguyen, Cu, Pandol, Stephen J, Teo, Jia-Ling, Wu, Kaijin, Wu, Yongfeng, Zhao, Yi   +12 more
core   +2 more sources

Identification of Novel Genetic Regulatory Region for Proprotein Convertase FURIN and Interferon Gamma in T Cells

Frontiers in Immunology, 2021
The proprotein convertase enzyme FURIN promotes the proteolytic maturation of pro-proteins and thereby it serves as an important factor for maintaining cellular homeostasis.
Zsuzsanna Ortutay, Anna Grönholm, Melina Laitinen, Melinda Keresztes-Andrei, Ismail Hermelo, Marko Pesu, Marko Pesu   +6 more
doaj   +1 more source

Prefronto-cerebellar transcranial direct current stimulation increases amplituded and decreases latency of P3b component in patients with euthymic bipolar disorder [PDF]

, 2015
INTRODUCTION: Neurocognitive impairments have been observed in patients with bipolar disorder (BD) even during the euthymic phase of the disease, potentially representing trait-associated rather than state-associated characteristics of the disorder.
BERNABEI, LAURA, BERSANI, FRANCESCO SAVERIO, BIONDI, Massimo, CORRADO, ALESSANDRA, DELLE CHIAIE, ROBERTO, FATTAPPOSTA, FRANCESCO, FRANCESCONI, MARTA, MANNARELLI, DANIELA, MINICHINO, AMEDEO, PAULETTI, CATERINA, Spagnoli, F, Taddei, I, VERGNANI, LUCILLA   +12 more
core   +2 more sources

Mutant and Wild-Type Tumor Suppressor p53 Induces p300 Autoacetylation

iScience, 2018
Summary: The transcriptional co-activator p300 is essential for p53 transactivation, although its precise role remains unclear. We report that p53 activates the acetyltransferase activity of p300 through the enhancement of p300 autoacetylation ...
Stephanie Kaypee, Smitha Asoka Sahadevan, Shilpa Patil, Piya Ghosh, Neeladri Sekhar Roy, Siddhartha Roy, Tapas K. Kundu   +6 more
doaj   +1 more source

p300 alters keratinocyte cell growth and differentiation through regulation of p21(Waf1/CIP1). [PDF]

PLoS ONE, 2010
p300 functions as a transcriptional co-activator to regulate many cellular responses such as cell growth, transformation, development and differentiation.
Ping-Pui Wong, Adam Pickard, Dennis J McCance   +2 more
doaj   +1 more source

BCIAUT-P300: A Multi-Session and Multi-Subject Benchmark Dataset on Autism for P300-Based Brain-Computer-Interfaces

Frontiers in Neuroscience, 2020
There is a lack of multi-session P300 datasets for Brain-Computer Interfaces (BCI). Publicly available datasets are usually limited by small number of participants with few BCI sessions.
M. Simões, D. Borra, Eduardo Santamaría-Vázquez, M. Bittencourt-Villalpando, D. Krzemiński, Aleksandar Miladinović, T. Schmid, Haifeng Zhao, Carlos P. Amaral, B. Direito, J. Henriques, P. Carvalho, M. Castelo‐Branco   +12 more
semanticscholar   +1 more source

Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapyResearch in context

EBioMedicine
Summary: Background: The E1A-associated protein p300 (p300) has emerged as a promising target for cancer therapy due to its crucial role in promoting oncogenic signaling pathways in various cancers, including prostate cancer.
Dize Zhang, Bohan Ma, Donghua Liu, Wei Wu, Tianyang Zhou, Yibo Gao, Cunli Yang, Yanlin Jian, Yizeng Fan, Yuchen Qian, Jian Ma, Yang Gao, Yule Chen, Shan Xu, Lei Li   +14 more
doaj   +1 more source