Results 61 to 70 of about 154,769 (339)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Musical rhythms and their influence on P300 velocity in young females Ritmos musicais diferentes: influência da velocidade no P300 em jovens mulheres

open access: yesBrazilian Journal of Otorhinolaryngology, 2011
Exposure to music may be useful in the P300 retest and avoid habituation. AIM: To verify the influence of the exposure to different kinds of music in P300 in young females. STUDY DESIGN: Clinical prospective.
Cintia Ishii de Sá   +1 more
doaj   +1 more source

Ergastava transkraniaalse magnetstimulatsiooni mõju petukäitumisele [PDF]

open access: yes, 2018
The present study investigated the effects of excitation of the dorsolateral prefrontal cortex (DLPFC) with repetitive transcranial magnetic stimulation (rTMS) on deceptive behaviour.
Uusen, Trine
core  

Phosphorylation of histone H3.3 at serine 31 promotes p300 activity and enhancer acetylation

open access: yesNature Genetics, 2019
The histone variant H3.3 is enriched at enhancers and active genes, as well as repeat regions such as telomeres and retroelements, in mouse embryonic stem cells (mESCs)1–3.
Sara Martire   +7 more
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Loss of p300 in proximal tubular cells reduces renal fibrosis and endothelial-mesenchymal transition

open access: yesEMBO Molecular Medicine
Chronic kidney disease (CKD) has a high prevalence worldwide and is typically accompanied by severe fibrosis. However, the exact pathogenesis of renal fibrosis and effective treatments have yet to be identified. In this study, we found that expression of
Hyunsik Kim   +9 more
doaj   +1 more source

Combining brain-computer interfaces and assistive technologies: state-of-the-art and challenges [PDF]

open access: yes, 2010
In recent years, new research has brought the field of EEG-based Brain-Computer Interfacing (BCI) out of its infancy and into a phase of relative maturity through many demonstrated prototypes such as brain-controlled wheelchairs, keyboards, and computer ...
Cincott, F.   +12 more
core   +7 more sources

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang   +9 more
wiley   +1 more source

P300 Component Modulation During a Go/Nogo Task in Healthy Children

open access: yesBasic and Clinical Neuroscience, 2010
Introduction: Several differences in the P300 component are observed when responses must be executed or inhibited in the Go/Nogo task. However, few studies were established by using well-controlled task with respect to the preparatory processing and ...
Mohammad Ali Nazari   +4 more
doaj   +2 more sources

CBP and p300 Jointly Maintain Neural Progenitor Viability but Play Unique Roles in the Differentiation of Neural Lineages

open access: yesCells, 2022
The paralogous lysine acetyltransferases 3 (KAT3), CBP and P300, play critical roles during neurodevelopment, but their specific roles in neural precursors maintenance and differentiation remain obscure.
Rocío González-Martínez   +5 more
doaj   +1 more source

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