Results 111 to 120 of about 2,898,090 (272)

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

The epigenetic landscape of plant defense: Unlocking nature's toolkit for new plant protection

open access: yesNew Plant Protection, EarlyView.
This review examines how epigenetic mechanisms regulate plant immune gene activation, repression, and priming, then links these natural regulatory layers to emerging epigenetic editing, discussing their potential for precise, heritable crop protection and the challenges.
Xuexia Liu, Zhenhui Zhong
wiley   +1 more source

Cognitive assessment in multiple sclerosis patients: electrophysiological and subjective studies

open access: yesThe Egyptian Journal of Otolaryngology
Background Multiple sclerosis (MS) is a persistent inflammatory condition affecting the central nervous system, often associated with cognitive impairment.
Abeer Elsayed   +3 more
doaj   +1 more source

Synchronized network activity as the origin of a P300 component in a facial attractiveness judgment task

open access: yes, 2014
Many studies have used the P300 as an index for cognitive processing and neurological/psychiatric disorders. Here, we combined the source separation and source localization methods to investigate the cortical origins of the P300 elicited in a facial ...
Zhou, Xiaolin   +2 more
core   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

open access: yesPhytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia   +6 more
wiley   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

open access: yesPhytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren   +10 more
wiley   +1 more source

Deep Learning Techniques for Classification of P300 Component

open access: yesProceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies, 2018
Jirí Vanek, Roman Moucek
openaire   +1 more source

Harnessing the Folding of Antitumor Peptides for Controlled Carrier‐Free Drug Delivery

open access: yesSmall, EarlyView.
A disulfide‐bridged stapled p53 α‐helix co‐assembled with doxorubicin into protease‐resistant nanocomplexes. Reductive intracellular conditions induced helix refolding and nanostructure disassembly, which enabled the coordinated release of the chemotherapeutic agent and anticancer peptide.
Jae Yun Lee   +9 more
wiley   +1 more source

Effects of Sleep Deprivation on Visual P300 [PDF]

open access: yes, 2006
睡眠剥夺在日常生活工作中广泛存在,导致认知功能下降,其中警觉水平下降最为明显。实验采用Oddball范式辨别任务,研究了32名青年男性在不同睡眠剥夺条件(sleep deprivation,SD)下(SD21h、SD45h、SD69h、正常对照组)的事件相关电位(event-related potentials,ERPs)P300成分的变化。结果表明,随SD时间延长,P300波幅降低、潜伏期延长 ...
宋国萍, 苗丹民, 赵仑, 皇甫恩
core   +1 more source

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