Results 161 to 170 of about 2,898,090 (272)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, Volume 20, Issue 10, Page 2510-2532, October 2026.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Baseline mathematical aptitude attenuates group differences in posterior P300 during arithmetic verification in high school athletes. [PDF]

Exp Brain Res
Hsu CC, Hsu HY, Ding TJ, Yao CY, Yao ZF.
europepmc   +1 more source

Targeting a Leukemia‐Relevant Protein–Protein Interface: N‐Aryl Anthranilic Acids as Disruptors of the c‐Myb–CBP/p300 KIX Interaction [PDF]

Chem Biol Drug Des
An integrated virtual screening, MD/MM‐PBSA, and MST workflow identifies N‐aryl anthranilic acids as disruptors of the leukemia‐relevant c‐Myb–CBP/p300 KIX interface. Hit C3 destabilizes the complex and inhibits c‐Myb–KIX binding more potently than Naphthol AS‐E phosphate.
Alfassam H, Kamel E, Othman S, Alharbi H, Rudayni H, Allam A, Lamsabhi A.   +6 more
europepmc   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, Volume 20, Issue 10, Page 2466-2489, October 2026.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Improving Selective Attention in Healthy Adults Through SMR Neurofeedback: Electrophysiological and Behavioral Evidence. [PDF]

Brain Sci
Stanković I, Jeličić L, Đorđević J, Ilić N, Sovilj M, Maksimović S, Marisavljević M, Subotić M.   +7 more
europepmc   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, Volume 13, Issue 56, 9 October 2026.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Present-Biased Preferences Associated with Socioeconomic Status in Intertemporal Decision-Making: Evidence from Behavioral and Electroencephalographic Measures. [PDF]

Brain Sci
Zhou H, Yang Y, Yi L, Xiang X, Liu Y.
europepmc   +1 more source

RESEARCH INTO THE P300 COMPONENT FOR VISUALLY METAPHORIC PICTURES

Bulletin of Japanese Society for the Science of Design, 2012
Wang, Regina W.Y., Chiu, Pei-Hua, Lee, Chia-Ying   +2 more
openaire   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Sex Differences Influence ERP Components in Semantic Decisions. [PDF]

Brain Sci
Gómez-Velázquez FR, Ruiz-Stovel VD, González-Medina C, Nava SA, Espinoza-Valdez A.   +4 more
europepmc   +1 more source