Results 1 to 10 of about 68,457 (172)

Heterozygous P32/C1QBP/HABP1 Polymorphism rs56014026 Reduces Mitochondrial Oxidative Phosphorylation and Is Expressed in Low-grade Colorectal Carcinomas

open access: yesFrontiers in Oncology, 2021
Rapid proliferation of cancer cells is enabled by favoring aerobic glycolysis over mitochondrial oxidative phosphorylation (OXPHOS). P32 (C1QBP/gC1qR) is essential for mitochondrial protein translation and thus indispensable for OXPHOS activity.
Annika Raschdorf   +7 more
doaj   +1 more source

Overexpression of Multifunctional Protein p32 Promotes a Malignant Phenotype in Colorectal Cancer Cells

open access: yesFrontiers in Oncology, 2021
p32 is a multifunctional and multicompartmental protein that has been found upregulated in numerous adenocarcinomas, including colorectal malignancy. High levels of p32 expression have been correlated with poor prognosis in colorectal cancer.
Carlos Alejandro Egusquiza-Alvarez   +7 more
doaj   +1 more source

p32/OPA1 axis-mediated mitochondrial dynamics contributes to cisplatin resistance in non-small cell lung cancer

open access: yesActa Biochimica et Biophysica Sinica, 2023
Cisplatin resistance is a major obstacle in the treatment of non-small cell lung cancer (NSCLC). p32 and OPA1 are the key regulators of mitochondrial morphology and function. This study aims to investigate the role
Yu Chun-Xia   +8 more
doaj   +1 more source

Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing. [PDF]

open access: yesPLoS ONE, 2013
Mammalian RNase H1 has been implicated in mitochondrial DNA replication and RNA processing and is required for embryonic development. We identified the mitochondrial protein P32 that binds specifically to human RNase H1, but not human RNase H2. P32 binds
Hongjiang Wu   +4 more
doaj   +1 more source

p32 promotes melanoma progression and metastasis by targeting EMT markers, Akt/PKB pathway, and tumor microenvironment

open access: yesCell Death and Disease, 2021
Melanoma originates from melanin-producing cells called melanocytes. Melanoma poses a great risk because of its rapid ability to spread and invade new organs. Cellular metastasis involves alteration in the gene expression profile and their transformation
Sunita Sinha   +4 more
doaj   +1 more source

An exceptional localization of hydatidosis

open access: yesPAMJ Clinical Medicine, 2020
A 48-years-old woman, presenting a huge mass of the posterior surface of the thigh, fixed on the deep and superficial planes, evolving for 1 year. The patient has no particular pathological history, and no other signs were noted, including neither weight´
Oussama Eladaoui, Abdelhak Garch
doaj   +1 more source

Carpo-metacarpal dislocation treatment

open access: yesPAMJ Clinical Medicine, 2020
We report the case of a young patient of 24 years, motorcyclist, victim of road accident, causing a closed trauma of the right wrist, the examination on admission finds a swollen, painful hand without vascular-nervous disorders, or compartment syndrome ...
Oussama Eladaoui, Abdelhak Garch
doaj   +1 more source

Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative ColitisSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell dysfunction have been attributed to the pathology of ulcerative colitis (UC).
Annika Sünderhauf   +16 more
doaj   +1 more source

Constraints in the Functioning of Primary Agricultural Cooperative Societies in Haryana State, India

open access: yesStudia Ekonomiczne i Regionalne, 2022
Subject and purpose of work: T he s tudy a ims t o identify t he constraints in t he f unctioning of PACS in Haryana, India.
Singh Suninder, Singh Abhey, Lal Choote
doaj   +1 more source

Mitochondrial import receptors for precursor proteins [PDF]

open access: yes, 1991
The specific targeting of precursor proteins synthesized in the cytosol to various cell organelles is a central aspect of intracellular protein traffic. Several hundred different proteins are imported from the cytosol into the mitochondria.
Attardi   +34 more
core   +1 more source

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