Results 1 to 10 of about 17,843 (182)

Post-traumatic radioulnar synostosis following forearm fracture osteosynthesis treated by excision and fascia lata interposition: A case report [PDF]

open access: yesTrauma Case Reports
Introduction: Post-traumatic radioulnar synostosis is a rare but severely disabling complication following forearm fractures, particularly after surgical fixation. It leads to loss of forearm rotation and major functional impairment.
Ismail Hssain   +4 more
doaj   +2 more sources

Overexpression of Multifunctional Protein p32 Promotes a Malignant Phenotype in Colorectal Cancer Cells

open access: yesFrontiers in Oncology, 2021
p32 is a multifunctional and multicompartmental protein that has been found upregulated in numerous adenocarcinomas, including colorectal malignancy. High levels of p32 expression have been correlated with poor prognosis in colorectal cancer.
Martha Robles-Flores   +1 more
exaly   +3 more sources

Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation

open access: yesCell Reports, 2018
Summary: Dendritic cell (DC) maturation induced by Toll-like receptor agonists requires activation of downstream signal transduction and metabolic changes. The endogenous metabolite citrate has recently emerged as a modulator of DC activation.
Takeshi Uchiumi   +2 more
exaly   +3 more sources

p32 is a negative regulator of p53 tetramerization and transactivation

open access: yesMolecular Oncology, 2019
p53 is a sequence‐specific transcription factor, and proper regulation of p53 transcriptional activity is critical for orchestrating different tumor‐suppressive mechanisms.
Tobias S Ulmer, Woojin An, Yonghwan Shin
exaly   +2 more sources

p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock

open access: yesEBioMedicine, 2017
Sepsis is a major cause of morbidity and mortality in seriously ill patients and mitochondrial dysfunction is associated with poor outcomes in septic patients. Although interleukin-6 (IL-6) is a good prognostic marker for sepsis, the relationship between
Takeshi Uchiumi   +2 more
exaly   +3 more sources

Interactions between sweetpotato Pushu 32 and soil factors shape starch accumulation, starch pasting, texture of starch and cooked storage roots, and cooked storage roots' sensory quality [PDF]

open access: yesFood Chemistry: X
Pushu 32 (P32) is an elite fresh-eating sweetpotato cultivar with prominent quality variation under diverse ecological soils. To clarify the multi-scale drivers of its quality across production areas, storage roots from 12 representative planting ...
Yue Fan   +9 more
doaj   +2 more sources

Heterozygous P32/C1QBP/HABP1 Polymorphism rs56014026 Reduces Mitochondrial Oxidative Phosphorylation and Is Expressed in Low-grade Colorectal Carcinomas

open access: yesFrontiers in Oncology, 2021
Rapid proliferation of cancer cells is enabled by favoring aerobic glycolysis over mitochondrial oxidative phosphorylation (OXPHOS). P32 (C1QBP/gC1qR) is essential for mitochondrial protein translation and thus indispensable for OXPHOS activity.
Annika Raschdorf   +7 more
doaj   +1 more source

Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing. [PDF]

open access: yesPLoS ONE, 2013
Mammalian RNase H1 has been implicated in mitochondrial DNA replication and RNA processing and is required for embryonic development. We identified the mitochondrial protein P32 that binds specifically to human RNase H1, but not human RNase H2. P32 binds
Hongjiang Wu   +4 more
doaj   +1 more source

p32 promotes melanoma progression and metastasis by targeting EMT markers, Akt/PKB pathway, and tumor microenvironment

open access: yesCell Death and Disease, 2021
Melanoma originates from melanin-producing cells called melanocytes. Melanoma poses a great risk because of its rapid ability to spread and invade new organs. Cellular metastasis involves alteration in the gene expression profile and their transformation
Sunita Sinha   +4 more
doaj   +1 more source

p32/OPA1 axis-mediated mitochondrial dynamics contributes to cisplatin resistance in non-small cell lung cancer

open access: yesActa Biochimica et Biophysica Sinica, 2023
Cisplatin resistance is a major obstacle in the treatment of non-small cell lung cancer (NSCLC). p32 and OPA1 are the key regulators of mitochondrial morphology and function. This study aims to investigate the role
Yu Chun-Xia   +8 more
doaj   +1 more source

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