Results 251 to 260 of about 218,916 (306)

Benzimidazolone p38 inhibitors

Bioorganic & Medicinal Chemistry Letters, 2004
The synthesis and in vitro p38 alpha activity of a novel series of benzimidazolone inhibitors is described. The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors ...
Mark A, Dombroski, Michael A, Letavic, Kim F, McClure, John T, Barberia, Thomas J, Carty, Santo R, Cortina, Csilla, Csiki, Alan J, Dipesa, Nancy C, Elliott, Christopher A, Gabel, Crystal K, Jordan, Jeff M, Labasi, William H, Martin, Kevin M, Peese, Ingrid A, Stock, Linne, Svensson, Francis J, Sweeney, Chul H, Yu   +17 more
openaire   +2 more sources

P38

Oral Diseases, 2005
Transferred to oral ...
openaire   +1 more source

p38 activation and viral infection

Expert Reviews in Molecular Medicine, 2022
AbstractViruses completely rely on the energy and metabolic systems of host cells for life activities. Viral infections usually lead to cytopathic effects and host diseases. To date, there are still no specific clinical vaccines or drugs against most viral infections. Therefore, understanding the molecular and cellular mechanisms of viral infections is
Luyao, Wang, Zhiqiang, Xia, Wei, Tang, Yu, Sun, Yingliang, Wu, Hang Fai, Kwok, Fang, Sun, Zhijian, Cao   +7 more
openaire   +2 more sources

p38

Surgery for Obesity and Related Diseases, 2006
Marlene M. Silva, Celina D.B. Sobreira, Alexandre Capeletto, Marta Magalinski, Cristiane E. Machado, Bruno Zilberstein, Denis Pajecki, Joel Faintuch   +7 more
  +4 more sources

P38

Journal of Surgical Research, 2007
S. Yeluri, N. Muthukumar, N.J. London
  +4 more sources