Results 231 to 240 of about 281,509 (352)

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

Molecular and Cellular Biology, 1996
J. Raingeaud, A. Whitmarsh, T. Barrett, B. Dérijard, R. Davis   +4 more
semanticscholar   +1 more source

Toll‐Like Receptors in the Mechanism of Hexabromocyclododecane‐Induced Production of Pro‐Inflammatory Cytokines

Journal of Applied Toxicology, EarlyView.
ABSTRACT Hexabromocyclododecane (HBCD), a brominated flame retardant, has raised increasing health concerns due to its bioaccumulation in human tissues and its ability to induce proinflammatory cytokines. Interleukin‐1β (IL‐1β), interleukin‐6 (IL‐6), and tumor necrosis factor‐α (TNF‐α) are major mediators of inflammation, and their chronic elevation ...
Wenjun Zhu, Aleshia Seaton‐Terry, Brian Townsend, Zinia Hunter, April Falconer‐Turner, Syeda Raika Shahid, Margaret Whalen   +6 more
wiley   +1 more source

A Dusty Affair: SIRT1-S682 Modulation Orchestrates ERK-FN1-p38-NF-κB Signaling and Composite-Dependent IL-8 Responses in Gingival Keratinocytes Exposed to Dental Dust and Eluates. [PDF]

J Funct Biomater
Bai S, Rau SJ, Steinberg T, Tomakidi P, Polydorou O.   +4 more
europepmc   +1 more source

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

EMBO Reports, 2001
K. Tobiume, A. Matsuzawa, Takumi Takahashi, H. Nishitoh, Kei-ichi Morita, K. Takeda, O. Minowa, K. Miyazono, T. Noda, H. Ichijo   +9 more
semanticscholar   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Intracellular NAD⁺ Depletion Increases Prostanoid Production via p38/COX2 Signalling in FK866-Induced Senescent Human Umbilical Vein Endothelial Cells. [PDF]

J Cell Mol Med
Kitajima N, Nakajo T, Katayoshi T, Tsuji K.   +3 more
europepmc   +1 more source

Perplexing p38 [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Semaglutide Inhibits Osteoblast Ferroptosis Induced by Diabetic Periodontitis via Modulating the Wnt5a/Ror2/p38 MAPK Signaling Pathway. [PDF]

Drug Des Devel Ther
Zhang Z, Niu D, Qiu W, Feng H, Jia L, Zhou W.   +5 more
europepmc   +1 more source

Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.

Cancer Cell, 2016
N. Lalaoui, Kay Hänggi, G. Brumatti, Diep Chau, N. Nguyen, Lazaros Vasilikos, Lisanne M. Spilgies, Denise A. Heckmann, Chunyan Ma, M. Ghisi, J. Salmon, Geoffrey M. Matthews, Elisha de Valle, Donia M. Moujalled, Manoj B. Menon, S. Spall, Stefan P. Glaser, J. Richmond, Richard B. Lock, Stephen M. Condon, R. Gugasyan, M. Gaestel, M. Guthridge, Ricky W. Johnstone, L. Munoz, A. Wei, P. Ekert, D. Vaux, W. Wong, J. Silke   +29 more
semanticscholar   +1 more source