Results 211 to 220 of about 229,819 (298)

Microbiota as the candidate biomarker in pediatric obstructive sleep apnea

open access: yesSleep Research, EarlyView.
Abstract Pediatric obstructive sleep apnea (OSA) is a form of sleep‐disordered breathing in children. Recent studies have focused on characterizing microbiota alterations associated with pediatric OSA and identifying microbial features that may have potential value as future biomarkers. The most commonly used approach for microbiota profiling is second‐
Xiaoyan Li   +4 more
wiley   +1 more source

Prunetin ameliorates myocardial pyroptosis after myocardial infarction by inhibiting the TNF-α/p38 MAPK/ERK pathway. [PDF]

open access: yesFront Cardiovasc Med
Wu H   +9 more
europepmc   +1 more source

Role of p38 MAPK in breast cancer

open access: yes, 2017
[spa] La proteína quinasa p38α está considerada como un supresor tumoral. Sin embargo, estudios recientes sugieren que puede promover el crecimiento y la supervivencia en algunos tipos de células tumorales, así como que su inhibición coopera con determinados agentes quimioterapéuticos.
openaire   +2 more sources

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

open access: yesVIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang   +7 more
wiley   +1 more source

YTHDF2 in hepatocellular carcinoma: Bridging m6A modification and cancer progression

open access: yesVIEW, EarlyView.
Abstract YTH N6‐methyladenosine RNAbinding protein F2 (YTHDF2) is an N6‐methyladenosine (m6A) reader protein that mainly regulates the stability of methylated transcripts through mRNA decay. In the liver, YTHDF2 is involved in metabolic homeostasis, oxidative stress responses, and immune regulation.
Sijie Zang   +7 more
wiley   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li   +12 more
wiley   +1 more source

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