Results 151 to 160 of about 84,309 (251)

Piezo1-mediated mechanotransduction in cementocytes via protein kinase B and p38 mitogen-activated protein kinase signaling. [PDF]

J Dent Sci
Xiong K, Sakisaka Y, Tenkumo T, Nemoto E, Maruyama K, Muhammad F, Suzuki S, Tada H, Yamada S.   +8 more
europepmc   +1 more source

Retracted: Improvement of Gut Microbiota by Inhibition of P38 Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Rats with Severe Acute Pancreatitis. [PDF]

Med Sci Monit, 2022
Wan YD, Zhu RX, Bian ZZ, Pan XT.
europepmc   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

Death of Leukemia Cells and Platelets Induced by 3,3'-Dihydroxy-4,5-Dimethoxybibenzyl Is Mediated by p38 Mitogen-Activated Protein Kinase Pathway. [PDF]

Molecules
Rukoyatkina N, Sokolova T, Pronin N, Whaley A, Whaley AO, Gambaryan S.   +5 more
europepmc   +1 more source

P38 Mitogen-Activated Protein Kinase Protects Against Retinoblastoma Through Regulating USP22/SIRT1/SOST Axis. [PDF]

Front Oncol, 2022
Huang X, Wan J, Liu F, Liu Y, Wang L, Zhao S, Wu T, Sun F.   +7 more
europepmc   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source

p38 mitogen-activated protein kinase drives senescence in CD4⁺ T lymphocytes and increases their pathological potential. [PDF]

Immun Ageing
González-Osuna L, Fukada SY, Hernández-Cáceres MP, Luz-Crawford P, Cortez C, Rojas C, Carvajal P, Sierra-Cristancho A, Vernal R.   +8 more
europepmc   +1 more source

Reactive Oxygen Species-Dependent Activation of EGFR/Akt/p38 Mitogen-Activated Protein Kinase and JNK1/2/FoxO1 and AP-1 Pathways in Human Pulmonary Alveolar Epithelial Cells Leads to Up-Regulation of COX-2/PGE₂ Induced by Silica Nanoparticles. [PDF]

Biomedicines, 2023
Lin YJ, Yang CC, Lee IT, Wu WB, Lin CC, Hsiao LD, Yang CM.   +6 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Fibroblast Growth Factor 21 Promotes Vascular Smooth Muscle Cell Contractile Polarization via p38 Mitogen-Activated Protein Kinase-Promoted Serum Response Factor Phosphorylation. [PDF]

Research (Wash D C)
Zhu M, Zhu W, Pan J, Chen Z, Yan Y, Wang S, Zhang T, Yang X, Xu H, Kong X, Hu H, Xu S, Zhang X, Zhang B, Liao C, Duan Y, Yang S, Chen Y.   +17 more
europepmc   +1 more source