Results 341 to 350 of about 177,903 (366)

p38 Mitogen Activated Protein Kinase as a Therapeutic Target for Alzheimer's Disease

Journal of Molecular Neuroscience, 2002
The characteristic pathological hallmarks of Alzheimer's disease (AD) include neuritic plaques, neurofibrillary tangles, and inflammatory changes. Current therapies, such as molecules that target enhancing cholinergic activity, can improve cognitive function in the short term but, unfortunately, have no impact on progression of the disease.
openaire   +3 more sources

Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases

Science, 2002
G. Johnson, R. Lapadat
semanticscholar   +1 more source

Beyond PI3Ks: targeting phosphoinositide kinases in disease

Nature Reviews Drug Discovery, 2023
Joanna Triscott, John E Burke, Brooke M Emerling   +2 more
exaly  

Assays for JNK and p38 Mitogen-Activated Protein Kinases

2000
Michael Karin, Tatsuhiko Sudo
openaire   +3 more sources

Mitogen-activated protein kinases in apoptosis regulation

Oncogene, 2004
T. Wada, J. Penninger
semanticscholar   +1 more source

Biomechanical stress‐induced apoptosis in vein grafts involves p38 mitogen‐activated protein kinases

The FASEB Journal, 2000
M. Mayr, Chaohong Li, Y. Zou, U. Huemer, Yanhua Hu, Qingbo Xu   +5 more
semanticscholar   +1 more source

Cell cycle kinases as therapeutic targets for cancer

Nature Reviews Drug Discovery, 2009
Antonio Giordano
exaly  

The AMP‐activated protein kinase activator AICAR does not induce GLUT4 translocation to transverse tubules but stimulates glucose uptake and p38 mitogen‐activated protein kinases α and β in skeletal muscle

, 2003
K. Lemieux, D. Konrad, A. Klip, A. Marette   +3 more
semanticscholar   +1 more source

The nuts and bolts of AGC protein kinases

Nature Reviews Molecular Cell Biology, 2010
David Komander, Dario R Alessi
exaly  

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

Nature Reviews Drug Discovery, 2010
Klaus Strebhardt
exaly