Results 111 to 119 of about 3,933 (119)

New Insights into Pathogenesis and Management of Keratoacanthoma: A Narrative Review. [PDF]

open access: yesInt J Mol Sci
Hyeraci M   +13 more
europepmc   +1 more source

Actinic Keratosis and Human Papillomaviruses: may their relationship constitute a new approach for actinic keratosis management? [PDF]

open access: yesTumour Virus Res
De Francesco MA   +7 more
europepmc   +1 more source
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Silencing E6/E7 Oncoproteins in SiHa Cells Treated with siRNAs and Oroxylum indicum Extracts Induced Apoptosis by Upregulating p53/pRb Pathways

Applied Biochemistry and Biotechnology, 2023
E6 and E7 human papillomavirus (HPV) oncoproteins play a significant role in the malignant transformation of infected cervical cancer cells via suppression of tumour suppressor pathways by targeting p53 and pRb, respectively. This study aimed to investigate the anticancer effects of Oroxylum indicum (OI) leaves' methanol extract on SiHa cervical cancer
Noor Nabilah Talik Sisin   +4 more
openaire   +2 more sources

HPV18 E6 and E7 genes affect cell cycle, pRB and p53 of cervical tumor cells and represent prominent candidates for intervention by use peptide nucleic acids (PNAs)

Cancer Letters, 2004
Approximately 100% of cervical carcinomas are causally linked to infections with high-risk human papillomaviruses (HPVs), whose oncogenicity has been assigned to the continued expression of two early viral genes, E6 and E7. Reversal of the transformed phenotype by inhibiting E6/E7 gene expression therefore provides a suitable goal for tumor therapy. We
Klaus, Braun   +7 more
openaire   +2 more sources

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