Results 201 to 210 of about 740,817 (321)
Association of Tissue Selenium Level and p53 Expression in Breast Cancer [PDF]
, 2019 Sanaz Salar Amoli +4 more
openalex +1 more source
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
Involvement of PIAS1 in the Sumoylation of Tumor Suppressor p53 [PDF]
, 2001 Tomoaki Kahyo +2 more
openalex +1 more source
Advanced Science, EarlyView.Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao +14 more
wiley +1 more source
Sociodemographic factors associated with the perception of the role of community nursing staff
Atención PrimariaJessenia Flores +3 more
doaj +1 more source
Small-Molecule Antagonists of p53-MDM2 Binding: Research Tools and Potential Therapeutics [PDF]
, 2004 Lyubomir T. Vassilev
openalex +1 more source
Advanced Science, EarlyView.Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi +10 more
wiley +1 more source