Results 51 to 60 of about 1,463,960 (261)

Variational method to a fractional impulsive (p,q) $(p,q)$-Laplacian coupled systems with partial sub- (p,q) $(p,q)$ linear growth

open access: yesAdvances in Difference Equations, 2019
In this paper, by using the least action principle, an existence result of nontrivial weak solutions for a class of fractional impulsive coupled systems with (p,q) $(p,q)$-Laplacian is obtained if the nonlinear term has sub- (p,q) $(p,q)$ linear growth ...
Cuiling Liu, Xingyong Zhang, Junping Xie
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Some trapezoid and midpoint type inequalities via fractional ( p , q ) $(p,q)$ -calculus

open access: yesAdvances in Difference Equations, 2021
Fractional calculus is the field of mathematical analysis that investigates and applies integrals and derivatives of arbitrary order. Fractional q-calculus has been investigated and applied in a variety of research subjects including the fractional q ...
Pheak Neang   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Some inequalities for (p,q) $(p,q)$-mixed volume

open access: yesJournal of Inequalities and Applications, 2018
Lutwak, Yang, and Zhang introduced the concept of (p,q) $(p,q)$-mixed volume whose special cases contain the Lp $L_{p}$-mixed volume and the Lp $L_{p}$-dual mixed volume.
Bin Chen, Weidong Wang
doaj   +1 more source

Bi-Periodic (p,q)-Fibonacci and Bi-Periodic (p,q)-Lucas Sequences

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2023
In this paper, we define bi-periodic (p,q)-Fibonacci and bi-periodic (p,q)-Lucas sequences, which generalize Fibonacci type, Lucas type, bi-periodic Fibonacci type and bi-periodic Lucas type sequences, using recurrence relations of (p,q)-Fibonacci and (p,
Yasemin Taşyurdu   +1 more
doaj   +1 more source

Some approximation results by Bernstein-Kantorovich operators based on (p,q)-integers

open access: yes, 2015
In this paper, First we have given the modified form of (p,q)-analogues of Bernstein and Bernstein operators [21-23] and then we introduce a new analogue of Bernstein-Kantorovich operators which we call as (p,q)-Bernstein-Kantorovich operators. We discuss approximation properties for these operators based on Korovkin's type approximation theorem and we
Mursaleen, M.   +2 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

On post-quantum multiparameter Riemann–Liouville fractional integral inequalities with application

open access: yesJournal of Inequalities and Applications
Post-quantum integral inequalities involving the Riemann–Liouville fractional integral have a significant role in understanding and modeling systems with nonlocal interactions; anomalous diffusion and memory effects make them indispensable for addressing
Sobia Rafeeq   +4 more
doaj   +1 more source

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