Results 101 to 110 of about 140,326 (292)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Identification of candidate genes associated with cell wall digestibility and eQTL (expression quantitative trait loci) analysis in a Flint × Flint maize recombinant inbred line population

BMC Genomics, 2007
Background Cell-wall digestibility is the major target for improving the feeding value of forage maize. An understanding of the molecular basis for cell-wall digestibility is crucial towards breeding of highly digestible maize. Results 865 candidate ESTs
Wenzel Gerhard, Landbeck Matthias, Ouzunova Milena, Uzarowska Anna, Shi Chun, Lübberstedt Thomas   +5 more
doaj   +1 more source

A note on the chemical composition and in vitro digestibility of contrasting stover components of maize grown in climatically marginal conditions and harvested at differing maturities. [PDF]

, 2014
peer-reviewedThis study evaluated the nutritive value of three contrasting components of maize stover (leaf, upper stem, lower stem) at three harvest dates.
Doyle, Evelyn M., Lynch, J.P., O'Kiely, Padraig   +2 more
core  

P-310 Fatigue and digestive cancers: A monocentric prospective study [PDF]

Annals of Oncology, 2020
W. Ben Kridis, S. Khmiri, A. Feki, N. Toumi, A. Khanfir   +4 more
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

In vitro and in vivo nutrient digestibility in sheep of rations with and without residue from the extraction of tamarind pulp

Semina: Ciências Agrárias, 2015
This study evaluated the digestibility of nutrients by, and parameters associated with, in vitro fermentation using different inocula (sheep ruminal fluid and feces) as well as the in vivo digestibility in sheep that were fed rations with 50% concentrate
Luiz Juliano Valério Geron, Fabiana Gomes da Costa, Silvia Cristina de Aguiar, Jocilaine Garcia, Matheus Gonçalves Ribeiro, Lúcia Maria Zeoula, Ana Paula da Silva, Sheslei Ribeiro Pereira, Roberto Martins Silveira   +8 more
doaj   +1 more source

The application of low crude protein wheat-soyabean diets to growing and finishing pigs: 2. The effects on nutrient digestibility, nitrogen excretion, faecal volatile fatty acid concentration and ammonia emission from boars [PDF]

, 2005
peer-reviewedThis study received financial support from Telltech Ltd. (Wicklow, Ireland) and Enterprise Ireland (Dublin, Ireland).Diets containing 132, 152, 183 and 206 g/kg crude protein (CP) were fed to growing and finishing boars to evaluate the ...
Callan, J.J., Henry, R. W., Leek, A. B. G., O'Doherty, John V.   +3 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Pre- and Post-Treatment Assessment for the Anaerobic Digestion of Lignocellulosic Waste: P-graph

Chemical Engineering Transactions, 2018
Lignocellulosic waste is one of the most abundant and potential feedstocks for anaerobic digestion (AD), but the energy efficiency is limited by the lignocellulosic composition which is recalcitrant to biodegradation. Pre- treatment of feedstock and the post-treatment of biogas and digestate play a significant role in enhancing the AD efficiency as ...
Yee, Van Fan, Klemes, Jirí Jaromír, Lee, Chew Tin   +2 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source