Results 71 to 80 of about 5,347,103 (256)
Second-Generation P-Values, Shrinkage, and Regularized Models
Frontiers in Ecology and Evolution, 2019 Second-generation p-values (SGPVs) are a novel and intuitive extension of classical p-values that better summarize the degree to which data support scientific hypotheses.
Thomas G. Stewart, Jeffrey D. Blume
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Croatian Journal of Food Science and Technology, 2019 The broken fractions of rice cultivars improved for yield, grain quality, amylose content and tolerance to common production constraints consisting of FARO 44, FARO 52, NERICA L-34, NERICA L-19 and LOCAL RICE. The rice cultivars, Sorghum malt and soybean
MAMUDU HALIDU BADAU +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Confidence with confidence intervals
Indian Journal of Ophthalmology, 1997 When considering the results of a study that reports one treatment to be better than another, what the practicing ophthalmologist really wants to know is the magnitude of the difference between treatment groups. If this difference is large enough, we may
Thomas Ravi +3 more
doaj
Annals of Geophysics, 2016 Present study describes the statistical properties of aftershock sequences related with two major Nepal earthquakes (April 25, 2015, MW 7.8, and May 12, 2015, MW 7.2) and their correlations with the tectonics of Nepal Himalaya.
Prasanta Chingtham +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Revista Colombiana de Cirugía, 2005 La evaluación del beneficio de una terapia es crucial para decidir si un nuevo tratamiento debe ser usado. Los clínicos que utilizan los resultados de los experimentos clínicos para guiar su práctica médica necesitan herramientas útiles para evaluar la ...
Eduardo Torregroza-Diazgranados
doaj
Kick-Start for Connectivity – How to Implement Digital Platforms Successfully in Industry 4.0
Technology Innovation Management Review, 2019 Based on digitalization and interconnectedness, Industry 4.0 causes a structural change in the value creation processes, and thus reinforces the transformation of business processes and business models. One way for companies to cope with this development
Marie-Christin Schmidt +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source