Results 91 to 100 of about 2,076,709 (312)
Inference with Linear Equality and Inequality Constraints Using R: The Package ic.infer [PDF]
In linear models and multivariate normal situations, prior information in linear inequality form may be encountered, or linear inequality hypotheses may be subjected to statistical tests.
Ulrike Grömping
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Enjoy the Joy of Copulas: With a Package copula [PDF]
Copulas have become a popular tool in multivariate modeling successfully applied in many fields. A good open-source implementation of copulas is much needed for more practitioners to enjoy the joy of copulas.
Jun Yan
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
tolerance: An R Package for Estimating Tolerance Intervals [PDF]
The tolerance package for R provides a set of functions for estimating and plotting tolerance limits. This package provides a wide-range of functions for estimating discrete and continuous tolerance intervals as well as for estimating regression ...
Derek S. Young
core
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Регуляторные исследования и экспертиза лекарственных средств, 2018 The article highlights the issues related to indication of drug storage conditions. It describes the approaches to indicating temperature requirements and to interpretation of the term «dry place». The article also provides the recommendations on setting
I. A. Prokopov +3 more
doaj
Learning Bayesian Networks with the bnlearn R Package [PDF]
bnlearn is an R package (R Development Core Team 2010) which includes several algorithms for learning the structure of Bayesian networks with either discrete or continuous variables.
Marco Scutari
core
Package of interventions for rehabilitation: module 1: introduction
, 2023 ix, 22 p.The "Package of interventions for rehabilitation: Module 1 – Introduction" presents the conceptual framework, scope, development methodology and intended use of the World Health Organization’s Package of interventions for rehabilitation ...
World Health Organization
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