Results 231 to 240 of about 2,076,709 (312)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Color Variability of European Oak Veneer Packages: An Exploratory Colorimetric, Chemical, and X-Ray Diffraction Study. [PDF]

Molecules
Smolarek E, Szentner K, Jakubowicz J, Jarzębski M, Wieruszewski M.   +4 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Mixed methods investigation into provision of family rooms and support for parents admitted to psychiatric inpatient units and their children: Study protocol. [PDF]

PLoS One
Dunn A, Elsby-Pearson C, Kalus L, Oliver M, Ratcliffe E, Cartwright-Hatton S.   +5 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

AI-driven environmental performance index using deep autoencoders for monitoring sustainable development goals. [PDF]

iScience
Khan A, Shuangjie L, Alomair A, Almusallam N, Rehman ZU.   +4 more
europepmc   +1 more source

replicateFest: an R package and shiny app for analysis of T cell receptor repertoire data from the functional expansion. [PDF]

Front Immunol
Danilova L, Favorov AV, Smith KN, Cope L.   +3 more
europepmc   +1 more source

Integrative genomics and experimental validation identify a mechanosensitive gene signature associated with colorectal cancer liver metastasis. [PDF]

iScience
Yang T, Yuan Y, Li X, Wang J, Li C, Xu Z.   +5 more
europepmc   +1 more source