Results 31 to 40 of about 1,418,757 (266)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Warnings and packaging [PDF]

Tobacco Control, 2019
The current issue of Tobacco Control highlights recent developments in research related to tobacco packaging, including issues as diverse as health warnings, plain packaging, messaging and novel products. Since the implementation of the first pictorial cigarette warnings by Canada nearly two decades ago, to the first implementation of plain packaging ...
openaire   +2 more sources

Technologies of Brand Development and Positioning

Вестник Российского экономического университета имени Г. В. Плеханова, 2021
Market economy develops very fast in current conditions, which fosters the growth in the number of goods and services of one product group. It helps avoid monopoly, but at the same time it makes customer choice more difficult as they get lost in the vast
S. B. Baurina
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A high-resolution electrostatically actuated MEMS Fabry–Pérot tunable filter for LWIR imaging and sensing applications

Microsystems & Nanoengineering
The long-wave infrared (LWIR) band lies near the peak of natural thermal emission, enabling stable passive imaging without active illumination, and it also covers characteristic spectral features of many important materials, making it a key spectral ...
Tengfei Xu, Huipeng Yang, Haiyang Hou, Siyao Xu, Zhipeng Yao, Peng Wang, Longfei Li, Kun Zhang, Jicong Zhao   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Application of Convolutional Neural Network to Predict Anisotropic Effective Thermal Conductivity of Semiconductor Package

IEEE Access, 2022
With increasing complexity of design patterns in semiconductor package substrates caused by demand for high-power semiconductors, it is necessary to be able to predict the thermal properties according to the pattern. Classifying the patterns is important
Tae-Hyun Kim, Jeong-Hyeon Park, Ki Wook Jung, Jaechoon Kim, Eun-Ho Lee   +4 more
doaj   +1 more source