Results 61 to 70 of about 2,076,709 (312)

STRATEGIES FOR PACKAGE WASTE REDUCING THROUGH A RATIONAL AND EFFECTIVE DESIGN

open access: yesJournal of Industrial Design and Engineering Graphics, 2017
The paper presents a number of regulations which should be respected when designing a package. Package represents a large percent of the total waste, therefore we should focus on this ‘type’ of product to reduce the resources used and also to reduce the ...
Lucian Barsan, Anca Barsan
doaj   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Current Requirements for Information Content and Graphic Design of a Medicinal Product Package

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2019
Labeling is an important source of information about a medicinal product. The completeness and accuracy of labeling ensures correct identification, as well as safe and efficacious use of the product.
L. I. Mit'kina, Anastasiya K. Ericheva
doaj   +1 more source

The gridGraphics Package [PDF]

open access: yesThe R Journal, 2015
The gridGraphics package provides a function, grid.echo(), that can be used to convert a plot drawn with the graphics package to a visually identical plot drawn using grid. This conversion provides access to a variety of grid tools for making customisations and additions to the plot that are not possible with the graphics package.
openaire   +2 more sources

Building Predictive Models in R Using the caret Package [PDF]

open access: yes
The caret package, short for classification and regression training, contains numerous tools for developing predictive models using the rich set of models available in R.
Max Kuhn
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The AdMit Package [PDF]

open access: yes
This short note presents the R package AdMit which provides flexible functions to approximate a certain target distribution and it provides an efficient sample of random draws from it, given only a kernel of the target density function.
Hoogerheide, L.F.   +2 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Overview of Modern Power Electronics Integration Technology

open access: yesKongzhi Yu Xinxi Jishu, 2016
It described the relevant technologies of modern power electron ics integration on the basis of PEBB/IPEM common concepts. Both the package and interconnection techniques were introduced stressfully. The abroad and domestic research status anddeveloping
ZHANG Ming
doaj  

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