Results 121 to 130 of about 281,052 (341)

Fluorescence Label‐Free Doxorubicin Sensor Using Polystyrene Sulfonate as a Synthetic Receptor in Whispering Gallery Mode Microresonators

Advanced Sensor Research, EarlyView.
The illustration showcases resonant optical microsensors for Doxorubicin (DXR) detection, using polystyrene sulfonate (PSS) as a synthetic receptor. PSS is deposited as a nanometer‐thick layer on fluorescent microparticles via layer‐by‐layer assembly. DXR‐PSS interaction is depicted, highlighting its effect on the sensor's resonant modes.
Elena Maurina, Algı Domac, Mateusz Olszyna, Lars Dähne, Giuseppe Barillaro   +4 more
wiley   +1 more source

Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: clinical and immunological data of a phase I/II clinical trial [PDF]

, 2016
Vaccination with priming and expansion of tumour reacting T cells is an important therapeutic option to be used in combination with novel checkpoint inhibitors to increase the specificity of the T cell infiltrate and the efficacy of the treatment. In
Antonilli M, BARCHIESI, GIACOMO, BELLATI, FILIPPO, BENEDETTI PANICI, PIERLUIGI, CAPONNETTO, SALVATORE, Iadarola R, NAPOLETANO, Chiara, NUTI, Marianna, PIERELLI, LUCA, RAHIMI KOSHKAKI, HASSAN, RUGHETTI, Aurelia, RUSCITO, ILARY, VISCONTI, Valeria, ZIZZARI, ILARIA GRAZIA   +13 more
core   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

pH-responsive high-density lipoprotein-like nanoparticles to release paclitaxel at acidic pH in cancer chemotherapy

International Journal of Nanomedicine, 2012
Jae-Yoon Shin,1,* Yoosoo Yang,1,* Paul Heo,1 Ji-Chun Lee,1 ByoungJae Kong,1 Jae Youl Cho,1 Keejung Yoon,1 Cheol-Su Shin,2 Jin-Ho Seo,3 Sung-Gun Kim,4 Dae-Hyuk Kweon11Department of Genetic Engineering, College of Biotechnology and Bioengineering, and ...
Shin JY, Yang Y, Heo P, Lee JC, Kong BJ, Cho JY, Yoon K, Shin CS, Seo JH, Kim SG, Kweon DH   +10 more
doaj  

Polaprezinc reduces paclitaxel-induced peripheral neuropathy in rats without affecting anti-tumor activity

Journal of Pharmacological Sciences, 2016
Paclitaxel, an anticancer drug, frequently causes painful peripheral neuropathy. In this study, we investigated the preventive effect of polaprezinc on paclitaxel-induced peripheral neuropathy in rats.
Kuniaki Tsutsumi, Takanori Kaname, Haruka Shiraishi, Takehiro Kawashiri, Nobuaki Egashira   +4 more
doaj   +1 more source

NEOADJUVANT WEEKLY NAB-PACLITAXEL PLUS CARBOPLATIN FOLLOWED BY DOXORUBICIN PLUS CYCLOPHOSPHAMIDE WITH BEVACIZUMAB ADDED CONCURRENTLY TO CHEMOTHERAPY FOR OPERABLE TRIPLE-NEGATIVE INVASIVE BREAST CANCER [PDF]

, 1969
Jasgit C. Sachdev, Jessica N. Snider, Jeffrey W. Allen, Lee S. Schwartzberg, Robyn R. Young, Ahmed Javed, Matthew Smeltzer, Furhan Yunus, Carmel S. Verrier, Mohammad Jahanzeb   +9 more
openalex   +1 more source

Targeted therapies in the management of locally advanced and metastatic pancreatic cancer: a systematic review [PDF]

, 2018
Pancreatic cancer has a dismal prognosis particularly in patients presenting with unresectable tumors. We performed a bibliometric analysis of clinical trials for pancreatic cancer conducted between 2014-2016 focusing on patients that presented with ...
Biankin, Andrew V., Khachigian, Levon M., Parish, Christopher R., Sheahan, Anjali V.   +3 more
core   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Cyclosporine A Decreased Paclitaxel Resistance in Prostate Cancer Cells by Inhibiting MTDH Expression

American Journal of Men's Health
This study aims to investigate the effect and mechanism of cyclosporine A (CsA) on paclitaxel-resistant prostate cancer cells. Paclitaxel-resistant prostate cancer cell lines were established by gradual increment method.
Jiangtao Li, Yuzhi Li, Xiaohong Zhang, Kun Liu, Shiping Yang, Zhang Liu, Sheng Cao, Dongfei Ren, Menghui Cui, Jia Su, Zewang Zhen, Donghong Zhang   +11 more
doaj   +1 more source

ANTIGENICITY STUDY OF PACLITAXEL

The Journal of Toxicological Sciences, 1994
The antigenic property of paclitaxel was examined using its protein mixtures (paclitaxel + OVA, paclitaxel + GSA, paclitaxel + RSA) in guinea pigs and mice in comparison with ovalbumin (OVA) and the protein conjugate of 4-aminoantipriyne (AAP). The following results were obtained: 1.
Katsumi Ishikawa, Norimitsu Takahashi, Toshihito Kadota, Hisashi Kohmura, Shigeo Kawano   +4 more
openaire   +4 more sources