Results 151 to 160 of about 261,105 (346)

SNORA58 Facilitates Radioresistance via Suppressing JNK1‐Mediated Ferroptosis in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
In ESCC patients, SNORA58 exhibits heterogeneous expression patterns. Its aberrant overexpression stabilizes CTCF by inhibiting ubiquitin‐mediated degradation, leading to the attenuation of JNK1‐mediated ferroptosis induced by radiotherapy through disruption of intracellular iron homeostasis, and ultimately contributes to radioresistance ...
Yinli Zheng, Fangyi Liu, Yuhua Huang, Yanfen Feng, Xia Yang, Jinjun Wu, Xin Yang, Xuanhao Lin, Lives Jiang, Tingting Zeng, Yan Li, Xinyuan Guan, Yuanyuan Wang, Chunyan Chen, Jingping Yun   +14 more
wiley   +1 more source

Pharmacokinetic evaluation of paclitaxel, albumin-binding paclitaxel, and liposomal-encapsulated albumin-binding paclitaxel upon gastric subserosal administration

Frontiers in Pharmacology
Introduction: Systemic chemotherapy is typically administered following radical gastrectomy for advanced stage. To attenuate systemic side effects, we evaluated the effectiveness of regional chemotherapy using paclitaxel, albumin-paclitaxel, and liposome-
Yoontaek Lee, Sun Mi Park, In Ho Song, Bom Sahn Kim, Hyun Soo Park, Hyun Soo Park, Hyun Soo Park, Byung Seok Moon, Hyung-Ho Kim   +8 more
doaj   +1 more source

Estrogen Alleviates Sevoflurane‐Induced Neurotoxicity by Inhibiting ERα‐Tau Binding

Advanced Science, EarlyView.
Sevoflurane‐induced neurotoxicity exhibits sex differences, and estrogen can mitigate these effects; however, its protective action appears to be time‐window dependent, which may be related to the competitive binding of estrogen and Tau to ERα. Abstract Sevoflurane‐induced neurotoxicity is age‐dependent, but the role of sex differences is unclear ...
Feixiang Li, Bingqing Gong, Zichen Song, Nuo Yang, Yuming Liu, Jinqin Zhang, Dujuan Li, Yongyan Yang, Yonghao Yu   +8 more
wiley   +1 more source

Determination of New Anticancer Drug, Paclitaxel, in Biological Fluids by High Performance Liquid Chromatography

, 1994
Hajime MASE, Masaki Hiraoka, Atsushi Suzuki, H Nakanomyo   +3 more
openalex   +2 more sources

Recall Reaction of a Severe Local Peripheral Neuropathy After Paclitaxel Extravasation [PDF]

, 1996
Manuel Hidalgo, Jordi Moreno Benito, Rámón Colomer, Luis Paz‐Ares   +3 more
openalex   +1 more source

The Clinical Development of Paclitaxel: A Successful Collaboration of Academia, Industry and the National Cancer Institute [PDF]

, 1996
Ross C. Donehower
openalex   +3 more sources

A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease.

New England Journal of Medicine, 2004
G. Stone, S. Ellis, D. Cox, J. Hermiller, C. O'shaughnessy, J. Mann, M. Turco, R. Caputo, P. Bergin, Joel D Greenberg, J. Popma, M. Russell   +11 more
semanticscholar   +1 more source

CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1

Advanced Science, EarlyView.
CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang, Xin Yang, Lei Xing, Hang Chen, Fuming Xie, Bin Wang, Bowen Shi, Yan Yang, Junxia Chen   +8 more
wiley   +1 more source

REPRODUCTIVE AND DEVELOPMENTAL TOXICITY STUDIES OF PACLITAXEL (I) : Intravenous administration to rats prior to and in the early stages of pregnancy

, 1994
S Kai, Hisashi KOHMURA, E Hiraiwa, S Koizumi, K Ishikawa, Shigeo Kawano, Kohji KUROYANAGI, Norimichi Hattori, H Chikazawa, Hiroshi Kondoh   +9 more
openalex   +2 more sources

Targeted Degradation of sGRP78 Alleviates the Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
Soluble GRP78 (sGRP78) is identified as a novel tumor‐derived soluble factor that induces regulatory T cells (Treg). sGRP78 serves as an excellent serological biomarker for predicting the efficacy of neoadjuvant therapy in breast cancer patients. sGRP78 specifically binds to B cells, inducing the expression of IL‐10 and PD‐L1, thereby promoting Treg ...
Zhenghao Wu, Peng Zheng, Yunxiao Xiao, Qianheng Wang, Xin Pan, Xiaoqi Zhou, Yibing Lv, Junyi Xiao, Yong He, Tao Huang, Ping Lei   +10 more
wiley   +1 more source