Results 111 to 120 of about 291,802 (171)

Metabolomics analysis of different diameter classes of Taxus chinensis reveals that the resource allocation is related to carbon and nitrogen metabolism

BMC Plant Biology
Taxus chinensis (Taxus cuspidata Sieb. et Zucc.) is a traditional medicinal plant known for its anticancer substance paclitaxel, and its growth age is also an important factor affecting its medicinal value.
Liben Pan, Yi Li, Wen Zhao, Yushu Sui, Nan Yang, Longjie Liu, Yang Liu, Zhonghua Tang, Liqiang Mu   +8 more
doaj   +1 more source

Nab-paclitaxel, docetaxel, or solvent-based paclitaxel in metastatic breast cancer: a cost-utility analysis from a Chinese health care perspective

, 2015
George Dranitsaris,1 Bo Yu,2 Jennifer King,3 Satyin Kaura,3 Adams Zhang3 1Augmentium Pharma Consulting Inc., Toronto, ON, Canada; 2Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China; 3Celgene Corporation, Summit, NJ, USA ...
Yu B, King J, Dranitsaris G, Kaura S, Zhang A   +4 more
core  

Phylogenetics of paclitaxel biosynthesis genes in Taxus baccata, Taxus hybrids and allies

, 2020
APPROVED
openaire   +1 more source

Paclitaxel transporter characterization

Paclitaxel is a valuable chemotherapeutic compound naturally produced by Taxus species, but its commercial production in plant cell culture systems remains limited by poor secretion efficiency.
Bray, Aili
core   +1 more source

An Italian cost-effectiveness analysis of paclitaxel albumin (nab-paclitaxel) versus conventional paclitaxel for metastatic breast cancer patients: the COSTANza study

, 2013
Carlo Lazzaro,1 Roberto Bordonaro,2 Francesco Cognetti,3 Alessandra Fabi,3 Sabino De Placido,4 Grazia Arpino,4 Paolo Marchetti,5 Andrea Botticelli,5 Paolo Pronzato,6 Elisa Martelli7 1Studio di Economia Sanitaria, Milan, Italy; 2Public Hospital Trust ...
Bordonaro R, Cognetti F, Marchetti P, Martelli E, De Placido S, Lazzaro C, Pronzato P, Fabi A, Arpino G, Botticelli A   +9 more
core  

Studies on a strain of Kitasatospora sp. paclitaxel producer

, 2000
The strain P&U 22869, which produces paclitaxel and related taxanes, discovered during the course of endophytic actinomycetes screening on Taxus baccata plants, was classified as Kitasatospora sp.
SARACCHI M., CARUSO M., CRESCPI-PERELLINO L., QUARONI S., FEDELI L., VENTRELLA G., COLOMBO A. L., MALYSZKO J., PAVESI A.   +8 more
core  

Metabolism of 7-epi-paclitaxel by Human Cytochrome P450 Enzymes: Effect of Epimer-epimer Interaction on the Metabolic Elimination of Paclitaxel

, 2008
-epi-paclitaxel is the principal degradant of paclitaxel under physiological conditions. Human liver microsomal incubation of 7-epi-paclitaxel in the presence of NADPH resulted in the formation of two monohydroxylated metabolites (M-1 and M-2), which ...
张延延, 张江伟, 葛广波, 刘勇, 杨凌   +4 more
core  

Species difference in paclitaxel disposition correlated with poor pharmacological efficacy translation from mice to humans

, 2018
Ying Fei Li,1 Chengyue Zhang,1 Simon Zhou,1 Miao He,2 Huixia Zhang,2 Nianhang Chen,1 Feng Li,2 Xin Luan,2 Manjunath Pai,3 Hebao Yuan,2 Duxin Sun,2 Yan Li1 1Translational Development and Clinical Pharmacology, Celgene Corporation, Summit, NJ 07901, USA ...
Luan X, Chen N, Pai M, Li Y, Zhou S, Zhang H, Li F, He M, Sun D, Zhang C, Yuan H, Li YF   +11 more
core  

Identification of rate-limiting enzymes involved in paclitaxel biosynthesis pathway affected by coronatine and methyl-β-cyclodextrin in Taxus baccata L. cell suspension cultures. [PDF]

Daru, 2018
Kashani K, Jalali Javaran M, Sabet MS, Moieni A.   +3 more
europepmc   +1 more source

Epigenetic Landscape and Regulation of Secondary Metabolite Accumulation Implicated in Anticancer and Nutraceuticals. [PDF]

Epigenomes
Kosaraju D, Jarapala VN, Yeddala A, Polavarapu C, Singareddy V, Palakolanu SR, Sreenivasulu N, Kishor PBK.   +7 more
europepmc   +1 more source