Results 51 to 60 of about 4,550 (174)

Xuming Zhusan Decoction Attenuates Post‐Stroke via Modulating TLR4/MYD88/NF‐κB Pathway in Mice

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
High‐dose Xuming Zhusan (XMZS) improves neurological/cognitive functions and reduces cerebral infarct in MCAO mice. It inhibits microglial activation and pro‐inflammatory cytokines via suppressing the TLR4/MYD88/NF‐κB pathway, protecting neurons. ABSTRACT Ischemic stroke induces neuroinflammation that exacerbates neuronal damage.
Xi Liu, Cheng Wang, Ling Han, Yi'an Xiao, Hanchang Yu, Zhongxu Hu, Xiyun Fei, Min Peng, Jilin Zhou, Zhijun Zhong   +9 more
wiley   +1 more source

Prospective Approaches to the Sustainable Use of Peonies in Bulgaria

Plants
In Europe, Paeonia officinalis and P. peregrina, along with Chinese P. lactiflora, are commonly used for medicinal purposes. This comprehensive review summarizes the secondary metabolites and biological activities of P. peregrina, P.
Christina Stoycheva, Daniela Batovska, Giuseppe Antonio Malfa, Rosaria Acquaviva, Giancarlo Statti, Ekaterina Kozuharova   +5 more
doaj   +1 more source

Jiawei Danxuan Koukang and Its Component Kaempferol Alleviate Oral Submucous Fibrosis by Restoring Epithelial‐Fibroblast Homeostasis and Suppressing Neutrophil Recruitment via the ANXA1/FPR2 Axis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
JDK and kaempferol upregulate ANXA1 in oral epithelia, which bind to fibroblast FPR2 to suppress myofibroblast activation, and collagen deposition, while reducing neutrophil recruitment and inflammation, thereby restoring epithelial‐fibroblast homeostasis to alleviate arecoline‐induced OSF. ABSTRACT Oral submucous fibrosis (OSF) is a betel quid chewing‐
Yao Xiao, Yisi Tan, Yanli Liu, Ruiyi Chen, Tao Zhou, Zhaoyong Hu, Jin Tan   +6 more
wiley   +1 more source

Immunomodulatory insights of monoterpene glycosides in endometriosis: immune infiltration and target pathways analysis

Hereditas
Endometriosis is a complex gynecological condition characterized by abnormal immune responses. This study aims to explore the immunomodulatory effects of monoterpene glycosides from Paeonia lactiflora on endometriosis.
Jin Zhan, Jiajie Wu
doaj   +1 more source

Tongxinluo for the Secondary Prevention of Atherosclerotic Disease: A Systematic Review and Meta‐Analysis of Randomized Clinical Trials

Brain and Behavior, Volume 16, Issue 3, March 2026.
This systematic review and meta‐analysis aims to evaluate the efficacy of tongxinluo in the secondary prevention of atherosclerotic cardiovascular disease (ASCVD). In summary, among patients with ASCVD, tongxinluo was associated with a trend toward a reduced incidence of stroke and a 28% lower risk of major adverse cardiovascular events (MACE), which ...
Yanyan Feng, Zhaobo Shi, Jiewen Zhang, Jiejie Li   +3 more
wiley   +1 more source

Progress on the Protective Effect and the Mechanism of Chinese Medicine Injection and Chinese Medicine Monomeric Small Molecules on Sepsis‐Related Liver Injury

Gut Medicine, Volume 2, Issue 1, Page 40-57, March 2026.
ABSTRACT Sepsis‐related liver injury (SRLI) involves multiple interrelated pathological processes, including excessive inflammation, oxidative imbalance, mitochondrial dysfunction, dysregulated autophagy, and microcirculatory impairment. Increasing evidence indicates that traditional Chinese medicine (TCM)–based interventions, particularly Chinese ...
Xiang Yunsheng, Yan Yumeng
wiley   +1 more source

Multi-Omics Analysis Reveals Key Regulators and Candidate Enzymes in the Biosynthesis of Albiflorin in Paeonia lactiflora

Horticulturae
Paeonia lactiflora is an important traditional Chinese medicine. Its core bioactive component, albiflorin, exhibits significant pharmacological activity, but its biosynthetic pathway remains unclear, severely limiting the targeted regulation and ...
Chunlan Peng, Yuan Zhou, Xuanyu He, Chenghua Gong, Juan Zhang, Chongbo Sun, Linying Li, Guoyan Zhao, Yuqing He, Xueying Zhang, Jianzhi Pan, Mingqi Liu, Gaojie Hong, Yanping Zhao   +13 more
doaj   +1 more source

Albiflorin Relieves Intervertebral Disc Degeneration Through Inhibiting Nucleus Pulposus Cell via the p38 MAPK/NF‐κB Pathway

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background As a chronic musculoskeletal disorder, intervertebral disc degeneration (IDD) is a leading cause of low back pain. Inflammatory response plays a key role in the IDD progression. Albiflorin (AF), a bioactive compound derived from Paeonia lactiflora, exhibits anti‐inflammatory effects in various diseases. However, the effects of AF on
Kai Yang, Yanping Cheng, Dan Yang
wiley   +1 more source

Identification and content analysis of volatile components in 100 cultivars of Chinese herbaceous peony

Ornamental Plant Research
Herbaceous peony (Paeonia lactiflora Pall.) is a well-known and traditional flower in China, occupying a significant position in Chinese traditional culture. The floral scent of the herbaceous peony however remains relatively understudied.
Aixin Wang, Yasang Luo, Tongfei Niu, Kai Gao, Sitong Wang, Xiaoyang Zhao, Xiaogai Hou, Lili Guo   +7 more
doaj   +1 more source

In Vitro Evaluation of the Inhibitory Effects of Linarin on Histamine‐Induced Expression of Proinflammatory Cytokines, Mucin 5AC, and Aquaporin 5 in Human Nasal and Bronchial Epithelial Cells

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 3, March 2026.
ABSTRACT Allergic rhinitis and asthma are two prevalent chronic allergic conditions in children. Linarin, a glycosylated flavonoid derived from various plants, exhibits a wide range of biological activities. This study aimed to investigate the therapeutic potential of linarin against allergic rhinitis and asthma.
Xin‐Jing Mi, Jie Wang, Jian‐Qiang Qi
wiley   +1 more source