Results 131 to 140 of about 4,897 (175)

Detection of Paeoniflorin and Albiflorin by Immunostaining Technique Using Anti‐Paeoniflorin Monoclonal Antibody

Phytochemical Analysis, 2012
ABSTRACTIntroductionPaeoniae radix is one of the most important crude drugs used in Kampo medicines (KMs). A part of its pharmaceutical properties is due to the presence of paeoniflorin (PF) and albiflorin (AF).ObjectiveFor the specific and easy identification of PF and AF, an immunostaining technique was developed using anti‐PF monoclonal antibody ...
Osamu, Morinaga, Zhaohua, Lu, Lidong, Lin, Takuhiro, Uto, Suphattra, Sangmalee, Waraporn, Putalun, Hiroyuki, Tanaka, Yukihiro, Shoyama   +7 more
openaire   +2 more sources

Involvement of Multitargets in Paeoniflorin-Induced Preconditioning

The Journal of Pharmacology and Experimental Therapeutics, 2006
Paeoniflorin (PF) is the principal component of Paeoniae radix prescribed in traditional Chinese medicine. The delayed neuroprotection induced by PF preconditioning and its underlying mechanisms were investigated in rat middle cerebral artery occlusion (MCAO) and reperfusion model.
Dong-Mei, Chen, Liang, Xiao, Xin, Cai, Rong, Zeng, Xing-Zu, Zhu   +4 more
openaire   +2 more sources

Effect of paeoniflorin on distal survival of random flaps

International Immunopharmacology, 2022
Distal ischemic necrosisis a common complication of orthopedic random skin flaps surgery. Paeoniflorin, a natural compound extracted from Paeonia lactiflora, can enhances angiogenesis and alleviates excessive inflammatory response. We investigated the changes of ischemic extra-long flaps with paeoniflorin and its possible mechanism.We raised dorsal ...
Wen-Jie, Li, Ying-Ying, Liu, Ji-Bing, He, Xin-Yi, Ma, Yi, Lin, Peng, Zheng, Ding-Sheng, Lin   +6 more
openaire   +2 more sources

Paeoniflorin attenuates allergic inflammation in asthmatic mice

International Immunopharmacology, 2015
Paeoniflorin (PF), one of the major active ingredients of Chinese peony, has demonstrated anti-inflammatory and immunoregulatory effects. However, it has remained unclear whether PF treatment can inhibit allergic inflammation in asthma. In this study, we evaluated the effects of PF on pulmonary function and airway inflammation in asthmatic mice.
Qingli Luo, Jingcheng Dong, Jing Sun
exaly   +3 more sources

Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora

Fìtoterapìâ, 2004
Paeoniflorin (1), isolated from the methanol extract of Paeonia lactiflora, showed a lowering effect on cholesterol level in the experimentally-induced hyperlipidemic rats. Paeoniflorin showed a significantly lowering effect of total cholesterol, LDL and triglyceride levels compared with the control group at the dose of 200 and 400 mg/kg, p.o.
Jae Youn Kim
exaly   +3 more sources

Paeoniflorin suppresses IL-33 production by macrophages

Immunopharmacology and Immunotoxicology, 2020
Objective: Interleukin (IL)-33 has been attracting more and more attention as a new member of theIL-1 cytokine family in recent years. However, the underlying mechanisms referred to the regulation of endogenous IL-33 production are not fully illustrated.
Weihua Li, Wenting Tao, Jiaojiao Chen, Yi Zhai, Nina Yin, Zhigang Wang   +5 more
openaire   +2 more sources

Development of Fluorescence-Linked Immunosorbent Assay for Paeoniflorin

Journal of Fluorescence, 2015
In this study, we developed a fluorescent immunoassay approach to detect paeoniflorin (PF) using a fluorescently labelled monoclonal antibody. The PF-specific antibody was purified by the caprylic acid-ammonium sulfate method and protein G Sepharose 4 Fast Flow column and then labelled with fluorescein isothiocyanate (FITC).
Yan, Zhao, Huihua, Qu, Xueqian, Wang, Yue, Zhang, Jinjun, Cheng, Yan, Zhao, Qingguo, Wang   +6 more
openaire   +2 more sources

The interactions of paeoniflorin and veratrine on isolated rat atria

Journal of Ethnopharmacology, 1997
In this study, we attempted to identify the interactions and mechanisms between veratrine and paeoniflorin on isolated rat atria. Paeoniflorin alone showed no effect on the rat atria. Veratrine increased the atrial contraction and induced arrhythmia at 1 x 10(-5) g/ml. Veratrine could directly induce contraction and elicit tetanic contraction at 1 x 10(
H Y, Tsai, Y T, Lin, Y F, Chen, C F, Chen   +3 more
openaire   +2 more sources

Synthesis and antioxidant activity of paeoniflorin derivatives

Bioorganic Chemistry
Paeoniflorin has multiple protective effects on the nervous system. However, its low bioavailability limits the exertion of its efficacy. In this study, a series of esterified derivatives of the alkyl groups of paeoniflorin were designed and synthesized through the strategies of group protection and alkyl acylation.
Qian, Xiao, YuXiang, Song, Meng, Yang, MingTao, Wang, HaiYi, Gao, XinYue, Zheng, Peiliang, Dong, Hua, Han   +7 more
openaire   +2 more sources

Effects of veratrine and paeoniflorin on the isolated rat aorta

Journal of Ethnopharmacology, 1999
The interactions and mechanisms between veratrine and paeoniflorin on the isolated rat aorta were studied. Veratrine (1x10(-6) to 1x10(-4) g/ml) could induce contraction on the isolated rat aorta in a concentration-related manner. Paeoniflorin had no effect on the isolated rat aorta.
H Y, Tsai, Y T, Lin, C F, Chen, C H, Tsai, Y F, Chen   +4 more
openaire   +2 more sources