Results 81 to 90 of about 2,661 (192)
Frontiers in Cardiovascular Medicine, 2022 BackgroundThis study primarily explored the role of paeonol in doxorubicin (DOX)-induced chronic heart failure (CHF), considering the cardioprotective effect of paeonol on an epirubicin-induced cardiac injury.MethodsDOX-induced CHF-modeled rats were ...
Cong Chen +9 more
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Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives
Precision Medical Sciences, Volume 15, Issue 3, Page 206-226, September 2026.Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
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ChemistrySelect, Volume 11, Issue 36, 22 September 2026.Burmannic acid (BURA) boosts radiosensitivity in oral cancer: combined with x‐rays, it suppresses tumor growth while sparing normal cells by increasing reactive oxygen species (ROS, MitoSOX), causing G2/M arrest, sub‐G1 accumulation, mitochondrial dysfunction, DNA damage, and apoptosis; these effects are reversed by N‐acetylcysteine. Therefore, BURA is
Kun‐Han Yang +9 more
wiley +1 more source
Insight into the immunomodulatory and chemotherapeutic mechanisms of paeonol (Review). [PDF]
Med Int (Lond)Paeonol a, pharmacologically active constituent obtained from the root bark of Paeonia suffruticosa has been extensively utilized as a traditional Chinese medicine for the treatment, prevention and control of several diseases for years. Paeonol has been reported to possess key immunomodulatory properties; however, the underlying mechanisms involved in ...
Barnes P +7 more
europepmc +3 more sources
eFood, Volume 7, Issue 4, August 2026.Schematic diagram of the mechanism by which Moutan Cortex extract (MCE) ameliorates DR. MCE alleviates retinal structural damage and reduces neovascular lesions by downregulating the ROS/HIF‐1α/VEGF signaling axis. ABSTRACT Moutan Cortex is a functional food ingredient with multiple health benefits, but its effects on diabetic retinopathy (DR) remain ...
Mei‐rong Li +13 more
wiley +1 more source
Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease
Food Science &Nutrition, Volume 14, Issue 7, July 2026.This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
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Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms
Phytotherapy Research, Volume 40, Issue 7, Page 4041-4055, July 2026.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
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Natural Products as Modulators of ABC Transporters in Breast Cancer
Phytotherapy Research, Volume 40, Issue 7, Page 4611-4637, July 2026.ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
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Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis
eFood, Volume 7, Issue 3, June 2026.Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng +5 more
wiley +1 more source
, 2022 Fungal populations are commonly found in natural environments and present enormous health care challenges, due to increased resistance to antifungal agents.
Ting Wang (16292) +5 more
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