Results 51 to 60 of about 117,142 (268)

Effects of Platelet-Activating Factor on Brain Microvascular Endothelial Cells. [PDF]

, 2018
Platelet-activating factor (PAF) is a potent phospholipid mediator that exerts various pathophysiological effects by interacting with a G protein-coupled receptor.
Abood, Mary E., Barlow, Christine L., Brailoiu, Eugen, Brailoiu, G. Cristina, Ramirez, Servio H.   +4 more
core   +1 more source

PifPaf: Composite Fields for Human Pose Estimation [PDF]

, 2019
We propose a new bottom-up method for multi-person 2D human pose estimation that is particularly well suited for urban mobility such as self-driving cars and delivery robots.
Alahi, Alexandre, Bertoni, Lorenzo, Kreiss, Sven   +2 more
core   +2 more sources

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Platelet activating factor levels and metabolism in tangier disease: a case study

Lipids in Health and Disease, 2012
Background Tangier disease (TD) is a phenotypic expression of rare familial syndrome with mutations in the ABCA1 transporter. The risk of coronary artery disease in patients with TD is variable.
Kolovou Vana, Papakonstantinou Vasiliki D, Stamatakis George, Verouti Sophia N, Xanthopoulou Marianna N, Kolovou Genovefa, Demopoulos Constantinos A   +6 more
doaj   +1 more source

Observing Pulsars with a Phased Array Feed at the Parkes Telescope

, 2017
During February 2016, CSIRO Astronomy and Space Science and the Max-Planck-Institute for Radio Astronomy installed, commissioned and carried out science observations with a phased array feed (PAF) receiver system on the 64m diameter Parkes radio ...
Chippendale, A. P., Dai, S., Deng, X., George, D., Hobbs, G., Johnston, S., Karuppusamy, R., Kramer, M., Malenta, M., Spitler, L., Tzioumis, T., Wieching, G.   +11 more
core   +1 more source

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier, Lukas Griesinger, Matthias Franzreb, Simon Kluters   +3 more
wiley   +1 more source

Targeting Platelet Activating Factor Signaling for Therapeutic Benefits in Neurodegenerative Disorders

Frontiers in Bioscience-Landmark
Neurodegenerative disorders (NDs), including dementia, Alzheimer’s disease (AD), and Parkinson’s disease (PD), are age-related diseases closely associated with chronic inflammation, oxidative stress, gene mutations, autoimmune-derived inflammation, and ...
Theodora Adamantidi, Andreas M. Grabrucker, Alexandros Tsoupras   +2 more
doaj   +1 more source

Association with the nonparoxysmal atrial fibrillation duration and outcome of ExTRa Mapping‐guided rotor ablation

Journal of Arrhythmia, 2023
Background Additional ablation strategies after pulmonary vein isolation (PVI) for patients with nonparoxysmal atrial fibrillation (non‐PAF) lasting ≥2 years have not been fully effective.
Yusuke Okuyama, Tomoya Ozawa, Takuma Nishikawa, Yusuke Fujii, Koichi Kato, Yoshihisa Sugimoto, Yoshihisa Nakagawa, Takashi Ashihara   +7 more
doaj   +1 more source

A Decision‐Making Model for Implementing Green Technology in Sustainable Building Projects

Business Strategy and the Environment, EarlyView.
ABSTRACT Green technology (GT) adoption is pivotal for reconciling environmental stewardship with economic viability in the built environment, particularly in resource‐constrained emerging economies. However, empirical evidence on how specific GT drivers actively mitigate adoption barriers remains scarce.
Abdelazim Ibrahim, Ahmed Farouk Kineber, Ayodeji Emmanuel Oke, Mehrdad Arashpour, M. K. S. Al‐Mhdawi, Abe Abimbola Maxwell   +5 more
wiley   +1 more source

Improving seismic signal classification of different ground activities with advanced AI and signal processing techniques

Discover Geoscience
This study presents a comparative framework for seismic signal classification based on adaptive decomposition and Hilbert spectral analysis. A self-recorded vibration dataset containing approximately 4,500 one-second segments of pedestrian, bicycle, and ...
Abdul Moiz, Mohsin Jadoon, Sohaib Ahmad, Arshad Iqbal, Muhammad Bilal Qureshi   +4 more
doaj   +1 more source