Results 71 to 80 of about 33,910 (244)

Current status and future perspectives of platelet function‐guided precision antiplatelet therapy for patients with cerebral infarction

Neuroprotection, EarlyView.
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu, Xiaoling Chen, Xinyi Huang, Quandan Tan, Qing Cao, Yali Yang, Yapeng Lin, Jie Yang   +7 more
wiley   +1 more source

NEURO-COGNITIVE AND PATHOPHYSIOLOGICAL CHANGES IN HYPOBARIC CHAMBER IN PILOTS OF PAKISTAN AIR FORCE

Pakistan Armed Forces Medical Journal, 2013
Objective: To determine the effects of hypoxia in hypobaric chamber and correlation of effects with time. Design: Descriptive study. Place and Duration of Study: Study was carried out at Aero medical Institute Masroor Base Karachi from July to December ...
Sq Ldr Sikandar Ali Khan, Kamran Adil ., Mansoor Mangi .   +2 more
doaj  

Peri‐urban agroforestry for climate mitigation in West Africa: Structural diversity and functional traits as key drivers of carbon storage

PLANTS, PEOPLE, PLANET, EarlyView.
Peri‐urban areas in West Africa are expanding rapidly, often with limited planning and growing exposure to climate risks. Our study shows that agroforestry systems in these landscapes, especially diverse home gardens, can store substantial amounts of carbon when they include structurally complex stands and species with traits that favor biomass ...
Sèdoami Flora Dogbo, Kolawolé Valère Salako, Sylvanus Mensah, Gafarou Agoundé, Kangbéni Dimobe, Achille Ephrem Assogbadjo, Jens Gebauer, Constant Yves Adou Yao, Romain Glèlè Kakaï   +8 more
wiley   +1 more source

Platelet-activating factor (PAF-acether) and microcirculation: effect of Lyso-PAF and PAF-antagonists.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 1988
Topical application of a standard dose of noradrenaline (NA) to the anesthetized rat mesentery evoked a vasoconstrictor response the latency of which was increased in a dose-dependent way by previous addition of PAF-acether or histamine but not by Lyso-PAF.
V, Lagente, Z B, Fortes, J, Garcia-Leme, B B, Vargaftig   +3 more
openaire   +1 more source

B-PAF

, 2020
El objetivo de este proyecto es realizar un intraemprendimiendo de la empresa B-PAF que permita diseñar la estrategia de expansión en el mercado de los Estados Unidos, mejorar los productos, e identificar de una mejor manera nuevas oportunidades de negocio que aporten valor a la empresa internacionalmente.
openaire   +1 more source

Host‐induced silencing of the Minc09294 effector gene impairs Meloidogyne incognita and M. Enterolobii infection

Pest Management Science, EarlyView.
Host‐induced gene silencing of the effector candidate Minc09294 significantly impairs Meloidogyne incognita parasitism, markedly reducing gall formation, reproduction, and the development of specialized giant cells, with partial cross‐species effects on M.
João Pedro Abreu‐Sousa, Thuanne Pires Ribeiro, Daniele Heloisa Pinheiro, Valdeir Junio Vaz Moreira, Luanna Pinheiro Alburquerque Freitas Bezerra, Júlia Moura Rosário Santana, Lays Antunes Teixeira, Maria Eugenia Lisei‐de‐Sa, Deyse Alexandra Rosero Alpala, Manoely Abreu Reis, Isabela Tristan Lourenço‐Tessutti, Leonardo Lima Pepino Macedo, Carolina Vianna Morgante, Maria Cristina Mattar Silva, Marcos Fernando Basso, Janice de Almeida‐Engler, Maria Fatima Grossi‐de‐Sa   +16 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source

INJECTION SCLEROTHERAPY VERSUS RUBBER BAND LIGATION FOR SECOND DEGREE HEMORRHOIDS

Pakistan Armed Forces Medical Journal, 2017
Objective: To compare the efficacy of injections Sclerotherapy (IST) and rubber band ligation (RBL) for the treatment of 2nd degree haemorrhoids in terms of improvement in symptoms severity score (SS score) in OPD patients.
Muhammad Ali Nasir, Rehan Masroor, Yasir Arafat, Qasim Butt, Shakil Sarwar   +4 more
doaj   +2 more sources

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source