Results 71 to 80 of about 11,309,322 (372)

On the Banks of the Amazon [PDF]

open access: yes, 2012
Published by Nelson, London. Page number(s) as given: not included in pagination.

core  

SNP-sites: rapid efficient extraction of SNPs from multi-FASTA alignments

open access: yesbioRxiv, 2016
Rapidly decreasing genome sequencing costs have led to a proportionate increase in the number of samples used in prokaryotic population studies. Extracting single nucleotide polymorphisms (SNPs) from a large whole genome alignment is now a routine task ...
A. Page   +6 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Jack Stanley [PDF]

open access: yes, 2012
Full title: Jack Stanley or, The Young Adventurers. Published by Warne, London. Page number(s) as given: not included in pagination.

core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

PAGE: Parametric Analysis of Gene Set Enrichment

open access: yesBMC Bioinformatics, 2005
BackgroundGene set enrichment analysis (GSEA) is a microarray data analysis method that uses predefined gene sets and ranks of genes to identify significant biological changes in microarray data sets.
Seon-Young Kim, David J. Volsky
semanticscholar   +1 more source

Large time blow up for a perturbation of the cubic Szeg\H{o} equation

open access: yes, 2014
We consider the following Hamiltonian equation on a special manifold of rational functions, \[i\p\_tu=\Pi(|u|^2u)+\al (u|1),\ \al\in\R,\] where $\Pi $ denotes the Szeg\H{o} projector on the Hardy space of the circle $\SS^1$. The equation with $\al=0$ was
Xu, Haiyan
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

'A Wish' [PDF]

open access: yes, 2012
Page number(s) as given: pp.404 ...

core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

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