Results 51 to 60 of about 1,691 (205)

Co-occurrence of apocrine adenocarcinoma and invasive mammary-type ductal carcinoma in extramammary Paget disease of the axilla

Archives of Plastic Surgery, 2020
Extramammary Paget disease (EMPD) is an uncommon malignancy that occurs in apocrine gland-rich areas of the body. EMPD of the axilla is rare, but a few cases have been reported.
Seung Bin Jang, Sung-Eun Kim, Young Ah Kim, Hye Ryeon Choi   +3 more
doaj   +1 more source

Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial Carcinoma

European Medical Journal, 2022
Extramammary Paget disease (EMPD) is a rare, cutaneous condition, which can present secondary to underlying carcinoma as an eczematoid rash that often mimics other conditions. Secondary EMPD should, therefore, be considered in the differential diagnosis
Victoria Dukharan, Adriana L Della Porta, Scott Gregory, Gulsun Erdag   +3 more
doaj   +1 more source

Vulvar Paget disease secondary to high-grade urothelial carcinoma with underlying massive vascular embolization and cervical involvement: case report of unusual presentation

Diagnostic Pathology, 2019
Background Vulvar extramammary Paget disease is a rare chronic condition, that presents with non-specific symptoms such as pruritus and eczematous lesions. Because most of these lesions are noninvasive, the distinction between primary and secondary Paget
Walquiria Quida Salles Pereira Primo, Guttenberg Rodrigues Pereira Primo, Dunya Bachour Basilio, Karime Kalil Machado, Jesus Paula Carvalho, Filomena M. Carvalho   +5 more
doaj   +1 more source

A clinicopathological analysis of forkhead box A1 (FOXA1) and estrogen receptor alpha expression in extramammary Paget’s disease

Fujita Medical Journal, 2023
Objectives: Extramammary Paget’s disease (EMPD) is a neoplastic skin disease of unknown etiology. EMPD is frequently associated with forkhead box A1 (FOXA1) expression, which correlates with the expression of estrogen receptor alpha (ER). FOXA1 regulates
Chiho Sumitomo, Yohei Iwata, Masaru Arima, Kazumitsu Sugiura   +3 more
doaj   +1 more source

Beyond the Ordinary: A Surgical Approach to Perianal Paget Disease

Journal of Coloproctology
Perianal Paget Disease (PPD) is a rare form of extramammary Paget disease characterized by erythematous or eczematous plaques in the perianal region. Its rarity and resemblance to benign skin conditions often result in delayed diagnosis.
Rita Ribeiro Dias, André Gonçalves, Joana Costa, Pedro Organista Machado, Eliane Jaconiano, Daniela Marinheiro Silva, Miguel Machado, Carolina Leal, Silvestre Carneiro   +8 more
doaj   +1 more source

A clinicopathological study of perianal paget disease: A single center-based cohort study and literature review

Dermatologica Sinica, 2022
Background: Perianal Paget disease (PPD), an uncommon extramammary Paget disease, is characterized by intraepidermal pagetoid spread of atypical Paget cells in the perianal skin. PPDs can be primary or secondary.
Ping-Chen Hou, Chaw-Ning Lee, Tak-Wah Wong, Tzu-Chien Hsu, Cheng-Lin Wu, Julia Yu-Yun Lee   +5 more
doaj   +1 more source

Paget's disease of the breast in a male with lymphomatoid papulosis: a case report [PDF]

, 2011
Introduction Paget's disease is an eczematous skin change of the nipple that is usually associated with an underlying breast malignancy. Male breast cancer represents only 1-3% of all breast malignancies and Paget's disease remains very rare.
Dina Fouad
core   +2 more sources

One‐year follow‐up after fractionated ultra‐high‐dose‐rate FLASH radiotherapy in patient with extramammary Paget disease of the scrotum

Precision Radiation Oncology, EarlyView.
An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo, Chengliang Yang, Ronghu Mao, Leijie Ma, Hongchang Lei, Peng Chen, Yanping Zhang, Meng Xu, Chao Wang, Yiwu Wang, Mingxia Wu, Chanjun Sun, Han Liu, Hui Liu, Hong Ge   +14 more
wiley   +1 more source

Perianal Paget's Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Perianal Paget's disease is rare and may be secondary to an underlying anorectal adenocarcinoma. Full‐thickness biopsy with immunohistochemistry is key to distinguish primary from secondary disease and to guide staging. Wide local excision is standard, while radiotherapy is a reasonable option when radical surgery is declined.
Daniela Lira, Maria Reigota Miranda, Marta Serra, Margarida Martins, Júlio Alves, Joana Noronha   +5 more
wiley   +1 more source

Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis

International Journal of Dermatology, Volume 65, Issue 3, Page 464-488, March 2026.
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla, Zseraldin Metyovinyi, Fanni Adél Meznerics, Arash Mirzahosseini, Judit Tőke, Miklós Tóth, Henriett Butz, Attila Patócs, Márta Medvecz   +8 more
wiley   +1 more source