Results 131 to 140 of about 136,040,587 (306)

Semelhanças e diferenças entre homens e mulheres na compreensão do comportamento paterno [PDF]

open access: yes, 2005
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Psicologia.O objetivo da presente pesquisa foi identificar a natureza da percepção de jovens adultos com e sem filhos ...
Prado, Alessandra Bonassoli
core  

The canonical e-box motif: a target for glucocorticoid action that drives rhythmic mouse Pai-1 transcription in vitro

open access: yes, 2008
Circadian (~ 24 h) control impinges on an array of diverse physiological processes in many organisms, ranging from plants to human. Disruption of the mammalian circadian clockwork can lead to severe chronic illnesses such as cardiovascular disease ...
Chong, Nelson W.   +3 more
core   +1 more source

Plasminogen Activation Inhibitor-1 Promotes Resilience to Acute Oxidative Stress in Cerebral Arteries from Females

open access: yesPharmaceuticals
Plasminogen activation inhibitor-1 (PAI-1) plays a central role in thrombus formation leading to stroke; however, the contributions of PAI-1 to cellular damage in response to reactive oxygen species which are elevated during reperfusion are unknown ...
Safa, Charles E. Norton
doaj   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu   +9 more
wiley   +1 more source

Primary tumor development and metastatic potential of PyMT mice crossed with PAI-1 WT or PAI-1−/− mice.

open access: yes, 2013
Presented results are from 11- and 14-week mice. (A): Tumor weight and (B): podoplanin positive relative surface in primary tumors observed in PAI-1 WT and PAI-1−/− mice.
Benoît Detry (366432)   +11 more
core   +1 more source

Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia

open access: yesHypertension in Pregnancy, 2019
Objective: Investigating D-Dimer/D-Di and plasminogen activator inhibitor type-1/PAI-1 levels throughout gestation in women with preeclampsia/PE risk factors. Methods: D-Di and PAI-1 plasma levels were determined in 28 women at 12–19, 20–29, 30–34 and 35–
Flávia Campos Lucena   +9 more
doaj   +1 more source

Axial Chirality Control Through Palladium‐Catalyzed Alkenylation Reactions for the Atroposelective Synthesis of 4‐Arylquinolin‐2‐ones

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Palladium(II)‐catalyzed intramolecular C─H alkenylation of cinnamides allows the atroposelective synthesis of axially chiral 4‐arylquinolones, with the chirality being installed by ring formation. DFT studies have shown that the reaction proceeds by prior activation of the alkene and the enantioselectivity is determined during the β‐hydride elimination
Brenda Fundora   +8 more
wiley   +1 more source

Raid, Doma Clásica, Salto de Obstáculos, Concurso Completo de Equitación [PDF]

open access: yes, 2017
Me es grato presentar el sexto Catálogo de Reproductores del Caballo de Deporte Español (CDE), en el que se recogen los animales que han alcanzado las Categorías Genéticas de Jóvenes Reproductores Recomendados, de Reproductores Mejorantes o ...
Cervantes Navarro, Isabel   +6 more
core   +1 more source

Role of the 4G/5G Polymorphism of PAI-1 Gene Promoter on PAI-1 Levels in Obese Patients

open access: yes, 2001
SummaryAs PAI-1, a cardiovascular risk factor linked to insulin-resistance, may be influenced by a 4G/5G gene polymorphism in disease states, we studied both PAI-1 plasma concentration (PAI-1:Ag) and 4G/5G polymorphism, and their relationship with ...
Paolo Della Mea   +9 more
core   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

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