Results 181 to 190 of about 69,700 (263)

Gambling disorder in late life: A systematic review of behavioral patterns, clinical correlates, and psychotherapeutic interventions

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Gambling in older adults represents an emerging but still underrecognized mental health concern. Although gambling participation is increasingly observed in later life, the specific psychological, social, cognitive, and biological factors associated with gambling‐related problems in older adults remain insufficiently ...
Graziella C. Prezzavento, Maria C. Quattropani, Vittorio Lenzo, Alberto Sardella, Chiara Franceschini, Giulia Galea, Pasquale Caponnetto   +6 more
wiley   +1 more source

Hexokinase 2-mediated histone H3K18la promotes PAI-1-dependent thrombosis in acute myeloid leukemia via tumor-endothelial crosstalk. [PDF]

Nat Commun
Bai Q, Qiu YX, Zeng H, Yao LH, Zhong FM, Xu YM, Zhang J, Huang B, Liu J, Shi H, Hou X, Wang ZH, Deng KY, Wang XZ.   +13 more
europepmc   +1 more source

Small Airways Dysfunction and Remission in Adults With Asthma: A Longitudinal Exploratory Analysis of the AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS) Study

Allergy, EarlyView.
We conducted a post hoc analysis of ATLANTIS, a multinational prospective study including 684 adults with asthma. Fewer small airway symptoms and lower disease activity are independently associated with asthma remission. Replicated airway transcriptomic signatures show increased IL‐4/13 signalling and reduced coagulation pathways across the ATLANTIS ...
Akshi Kumar, Rory Chan, Nazanin Zounemat‐Kermani, Eleanor Quek, Ian M. Adcock, Bianca Beghe, Christopher Brightling, Dave Singh, Janwillem Kocks, Alberto Papi, Klaus F. Rabe, Ulrica Scaffidi‐Argentina, Maarten van den Berge, Monica Kraft, Salman Siddiqui   +14 more
wiley   +1 more source

Serum miR-34a as Indicator of Impaired Fibrinolytic Capacity in Pediatric Thrombosis Through Inadequate Regulation of the ACE/PAI-1 Axis. [PDF]

Int J Mol Sci
Gintoni I, Baldouni K, Dettoraki A, Michalopoulou A, Papathanasiou I, Tsezou A, Vlachakis D, Pergantou H, Chrousos GP, Yapijakis C.   +9 more
europepmc   +1 more source

Clinical Features of Cellular Senescence Pathways in Severe Asthma

Allergy, EarlyView.
In bronchial biopsies, SASP and p53 pathway enrichment scores are elevated in severe asthma versus non‐severe asthma and healthy controls. SASP enrichment is validated in the independent NOVA cohort. SASP enrichment is also elevated in nasal brushings of participants with nasal polyps, independently of asthma status.
Woo‐Jung Song, Nazanin Zounemat Kermani, Ali Versi, Stephany Sánchez‐Ovando, Jodie Louise Simpson, Peter A. Wark, Katherine Joanne Baines, Sven‐Erik Dahlén, Ratko Djukanovic, Yike Guo, Ian M. Adcock, Kian Fan Chung, on behalf of the U‐BIOPRED Study Group, Mahmoud. I. Abdel‐Aziz, Ian M. Adcock, Lars I. Andersson, Charles Auffray, Yusef E. Badi, Per Bakke, Aruna T. Bansal, Frederic Baribaud, Stewart A. Bates, Elisabeth H. Bel, Jeanette Bigler, Bo Billing, Hans Bisgaard, Michael J. Boedigheimer, Klaus Bønnelykke, Joost Brandsma, Paul Brinkman, Enrica Bucchioni, Dominic Burg, Andrew Bush, Massimo Caruso, Romanas Chaleckis, Pascal Chanez, Kian Fan Chung, T. Checa, Chris H. Compton, Julie Corfield, Danen Cunoosamy, Arnaldo D'Amico, Barbro Dahlén, Sven‐Erik Dahlén, Bertrand De Meulder, Ratko Djukanovic, Veit J. Erpenbeck, Damijan Erzen, K. Fichtner, Louise J. Fleming, Elena Formaggio, Stephen J. Fowler, Urs Frey, Martina Gahlemann, Thomas Geiser, Victoria Goss, Yike Guo, Simone Hashimoto, John Haughney, Gunilla Hedlin, Pieter‐Paul W. Hekking, Timothy Higenbottam, Jens M. Hohlfeld, Cecile Holweg, Ildiko Horvath, Peter Howarth, Anna J. James, Richard G. Knowles, Johan Kolmert, Jon Konradsen, Norbert Krug, Nikos Lazarinis, C.‐X. Li, Matthew J. Loza, Rene Lutter, Alexander Manta, Sarah Masefield, Anke H. Maitland‐van der Zee, John G. Matthews, Alexander Mazein, Roelinde J. M. Middelveld, Montserrat Miralpeix, Paolo Montuschi, Jacek Musial, Sharon Mumby, David Myles, Björn Nordlund, Ioannis Pandis, Stelios Pavlidis, Anthony Postle, P. Powel, G. Praticò, M. Puig Valls, N. Rao, Stacey Reinke, John Riley, Amanda Roberts, Graham Roberts, Anthony Rowe, Thomas Sandström, Jim P. R. Schofield, Wolfgang Seibold, Dominic E. Shaw, R. Sigmund, Florian Singer, Paul J. Skipp, M. Smicker, Ana R. Sousa, Maria Sparreman‐Mikus, Peter J. Sterk, Marika Ström, Kai Sun, Bob Thornton, Mohib Uddin, Ali Versi, Jorgen Vestbo, Nadja H. Vissing, Scott S. Wagers, Åsa Wheelock, Craig E. Wheelock, Susan J. Wilson, Valentyna Yasinska, Nazanin Zounemat Kermani   +122 more
wiley   +1 more source

Role of plasminogen activator inhibitor-1 (PAI-1) in age-related cardiovascular pathophysiology. [PDF]

J Cardiovasc Aging
Khoddam A, Vaughan D, Wilsbacher L.
europepmc   +1 more source

Muralismo como encargo participativo: Holografía de lo (in)visible en comunidades a’i cofán de la selva colombiana

Anthropology of Consciousness, EarlyView.
ABSTRACT When mural art in indigenous communities is commissioned as a participatory project, several methodological, epistemological, and aesthetic questions arise. This text proposes a horizontal and investigative approach to what we can simply call ‘muralism in the A'i Cofán community context,’ not as significant works executed in communities, but ...
Daniel Alberto Restrepo Hernández, Andrés Rojas Guarín, Alexander Queta Criollo   +2 more
wiley   +1 more source

Association Between Follistatin and PAI-1 Levels in MASLD Subjects Undergoing a Plant-Based Dietary Intervention. [PDF]

Nutrients
Cerabino N, Bonfiglio C, Di Chito M, Donvito R, Mongelli FP, Pesole PL, Stabile D, Shahini E, Zappimbulso M, Cozzolongo R, Giannelli G, De Pergola G.   +11 more
europepmc   +1 more source

Mapping Palaeolithic Imprints: Spatial Analysis of Hand Stencils in El Castillo Cave (Spain) Through Geomatic Techniques

Archaeometry, EarlyView.
ABSTRACT We present the application of a new quantitative approach to space study in Palaeolithic cave art. Using GIS, we analysed the distribution and position of hand stencils in El Castillo cave to track the gestures and behaviours of Palaeolithic societies.
Olga Spaey, Iñaki Intxaurbe, Iñigo Urrestarazu‐Porta, Martin Arriolabengoa, Sergio Salazar, Verónica Fernández‐Navarro, Aritz Irurtzun, Diego Garate   +7 more
wiley   +1 more source

Hepatic AhR Activation by TCDD Induces Obesity and Steatosis via Hepatic Plasminogen Activator Inhibitor-1 (PAI-1). [PDF]

Int J Mol Sci
Oh SJ, Im S, Kang S, Lee AG, Lee BC, Pak YK.   +5 more
europepmc   +1 more source