Results 91 to 100 of about 1,697,378 (293)
From labor to surgery: expanding the role of programmed intermittent epidural bolus beyond obstetric [PDF]
Epidural analgesia has been effective for postoperative pain control, but its use has declined owing to adverse effects, such as motor blockade and delayed recovery.
Yu Jeong Bang, RyungA Kang
doaj +1 more source
Almost anyone with a limb amputation experiences phantom sensations. Moreover, the majority of amputees experience pain. This phenomenon is known as ‘Phantom pain’ and is described as the pain felt from a body part, usually a limb, which is no longer ...
Duca, Kristina, Muscat, Richard
core
VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang +7 more
wiley +1 more source
Background: The incidence of chronic postsurgical pain (CPSP) is relatively high after breast cancer surgery. Psychological factors, especially high pain catastrophising, are predictive of CPSP.
Aneurin Moorthy +5 more
doaj +1 more source
Efficacy of pectoral nerve II block for flap dissection-related pain following robot-assisted transaxillary thyroidectomy: a prospective, randomized controlled trial [PDF]
Background Robot-assisted transaxillary thyroidectomy (RATT) involves extensive flap dissection, leading to significant postoperative pain. This study evaluated the efficacy of pectoral nerve II (PECS II) block in pain relief, opioid reduction, and ...
Min Suk Chae, Kwangsoon Kim
doaj +1 more source
Three comparable groups of surgical patients were given nefopam 0.2 mg kg-1 or 0.4 mg kg-1 or morphine 0.15 mg kg-1 for pain relief after operation. Nefopam 0.4 mg kg-1 was equi-analgesic with morphine 0.15 mg kg-1 and produced no obvious cardiovascular or respiratory side-effects.
G, Phillips, M D, Vickers
openaire +2 more sources
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan +10 more
wiley +1 more source
Comparison of the effects of indomethacin, diclofenac and acetaminophen suppositories on pain score and pethedine usage after cesarean section [PDF]
Background : Cesarean section is one of the common surgeries of women. The rate of cesarean section over the west societies is currently about 14%-15%. In Iran the rate of cesarean section is higher than universal statistics. Acute postoperative pain is
اخوان اکبری, قدرت +2 more
core
Patient experiences of anxiety, depression and acute pain after surgery: a longitudinal perspective [PDF]
This study sought to explore the impact of the psychological variables anxiety and depression, on pain experience over time following surgery. Eighty-five women having major gynaecological surgery were assessed for anxiety, depression and pain after ...
Thomas, Veronica Nicky +5 more
core +1 more source
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong +17 more
wiley +1 more source

