The movement of sediment in a channel in relation to magnitude and frequency concepts- a New Zealand example [PDF]
In areas where surface wash contributes most of the debris to a channel network, the effect of events of moderate magnitude and frequency appear to be more important than catastrophic events for land form development.
Hosking, Peter L., Pain, C.F.
core +1 more source
Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier+8 more
wiley +1 more source
Injustice perceptions about pain: parent–child discordance is associated with worse functional outcomes [PDF]
Pain is experienced within and influenced by social environments. For children with chronic pain, the child–parent relationship and parental beliefs about pain are particularly important and may influence pain outcomes. Pain-related injustice perceptions
Hirsh, Adam T.+5 more
core +1 more source
Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies
ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik+5 more
wiley +1 more source
Machine-based Multimodal Pain Assessment Tool for Infants: A Review [PDF]
Bedside caregivers assess infants' pain at constant intervals by observing specific behavioral and physiological signs of pain. This standard has two main limitations. The first limitation is the intermittent assessment of pain, which might lead to missing pain when the infants are left unattended.
arxiv
Accounting for Affect in Pain Level Recognition [PDF]
In this work, we address the importance of affect in automated pain assessment and the implications in real-world settings. To achieve this, we curate a new physiological dataset by merging the publicly available bioVid pain and emotion datasets. We then investigate pain level recognition on this dataset simulating participants' naturalistic affective ...
arxiv
Diagnostic tools for 3D unstructured oceanographic data
Most ocean models in current use are built upon structured meshes. It follows that most existing tools for extracting diagnostic quantities (volume and surface integrals, for example) from ocean model output are constructed using techniques and software ...
Atkinson+12 more
core +1 more source
Goal pursuit in individuals with chronic pain: a personal project analysis [PDF]
Objectives: In individuals with chronic pain (ICPs), controlling pain often is a salient goal, despite the difficulty to achieve it. This situation may bring along frustration and distress.
Crombez, Geert+3 more
core +2 more sources
Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan+6 more
wiley +1 more source
Expanding the causal menu: An interventionist perspective on explaining human behavioural evolution
Theorists of human evolution are interested in understanding major shifts in human behavioural capacities (e.g. the creation of a novel technological industry, such as the Acheulean).
Ronald J. Planer, Ross Pain
doaj +1 more source