Results 71 to 80 of about 258,677 (299)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Spatial and temporal proximity as factors in shape recognition
Behavioral and Brain Functions, 2007 Prior research from this laboratory examined minimal stimulus conditions that allow for recognition of objects. Using briefly flashed dots that marked the outer border of objects, it was found that timing differentials within and among successive dot ...
Greene Ernest
doaj +1 more source
Glutamate-receptor-mediated encoding and retrieval of paired-associate learning [PDF]
Nature, 2003 Paired-associate learning is often used to examine episodic memory in humans. Animal models include the recall of food-cache locations by scrub jays and sequential memory. Here we report a model in which rats encode, during successive sample trials, two paired associates (flavours of food and their spatial locations) and display better-than-chance ...
Day, M., Langston, R., Morris, R. G. M.
openaire +4 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Neural Architecture Comparison for Bibliographic Reference Segmentation: An Empirical Study
DataIn the realm of digital libraries, efficiently managing and accessing scientific publications necessitates automated bibliographic reference segmentation.
Rodrigo Cuéllar Hidalgo +5 more
doaj +1 more source
Modelling Sentence Pairs with Tree-structured Attentive Encoder
CoRR, 2016 We describe an attentive encoder that combines tree-structured recursive neural networks and sequential recurrent neural networks for modelling sentence pairs. Since existing attentive models exert attention on the sequential structure, we propose a way to incorporate attention into the tree topology. Specially, given a pair of sentences, our attentive
Yao Zhou, Cong Liu 0001, Yan Pan 0002
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Stimulus encoding selectivity at high degrees of paired-associate learning [PDF]
Memory & Cognition, 1973 Sixty-two Ss learned six CCC trigram-digit pairs by the study-test method; 21 Ss continued the PA acquisition trials to a learning criterion of one errorless trial, while 41 Ss were carded to 300% overlearning or 24 trials, whichever came first. The Ss were then shown individual letters of the trigrams, with position cues provided, and were tested for ...
E A, Lovelace, J D, Savage
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source