Results 41 to 50 of about 403,679 (224)

Statistical methods for linguistic research: Foundational Ideas - Part I

open access: yes, 2016
We present the fundamental ideas underlying statistical hypothesis testing using the frequentist framework. We begin with a simple example that builds up the one-sample t-test from the beginning, explaining important concepts such as the sampling ...
Nicenboim, Bruno, Vasishth, Shravan
core   +1 more source

Task-Related modulations of BOLD low-frequency fluctuations within the default mode Network [PDF]

open access: yes, 2017
Spontaneous low-frequency Blood-Oxygenation Level-Dependent (BOLD) signals acquired during resting state are characterized by spatial patterns of synchronous fluctuations, ultimately leading to the identification of robust brain networks.
Daniele Mascali   +12 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Reference material comparisons: design of experiment and processing of measurement results

open access: yesСтандартные образцы, 2017
The present article describes general principles of experimental research and processing of measurement results within the framework of one of the methods of evaluating the interchangeability of reference materials - paired comparisons of reference ...
E. V. Osintseva
doaj  

A comparison of integrated testlet and constructed-response question formats

open access: yes, 2014
Constructed-response (CR) questions are a mainstay of introductory physics textbooks and exams. However, because of time, cost, and scoring reliability constraints associated with this format, CR questions are being increasingly replaced by multiple ...
Shiell, Ralph C., Slepkov, Aaron D.
core   +2 more sources

Mechanisms of cognitive-behavioral therapy for obsessive-compulsive disorder involve robust and extensive increases in brain network connectivity. [PDF]

open access: yes, 2017
Cognitive-behavioral therapy (CBT) is effective for obsessive compulsive disorder (OCD); however, little is understood about its mechanisms related to brain network connectivity.
Cheng, G   +7 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Validation and application of a tool to assess self-confidence to do improvement

open access: yesBMJ Open Quality
Introduction Increasing improvement capability in the workforce is vital within healthcare. The type of quality improvement training to increase capability varies. One way to measure the impact of improvement training is self-confidence to do improvement.
Annette Richardson, Jon Rees
doaj   +1 more source

Calcium-independent inhibitory G-protein signaling induces persistent presynaptic muting of hippocampal synapses [PDF]

open access: yes, 2011
Adaptive forms of synaptic plasticity that reduce excitatory synaptic transmission in response to prolonged increases in neuronal activity may prevent runaway positive feedback in neuronal circuits.
Chang, Chun Yun   +3 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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