Results 51 to 60 of about 169,356 (242)
, 2015 Comparisons performed by Cufflinks using treatment specific paired-samples from two biological replicates. All genes displayed were significantly differentially expressed due to a higher RPKM in Polymorphprep prepared samples. Significance was calculated
Steven W. Edwards (135244) +3 more
core +1 more source
BMC AnesthesiologyBackground Extended work hours contribute to fatigue among healthcare professionals, but their specific impact on anaesthesia providers remains poorly defined.
Annelies Scholliers +7 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Development and evaluation of statistical approaches in proteomic biomarker discovery [PDF]
, 2011 A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes or pharmacological responses to a therapeutic intervention.
Patel, Amit
core
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Online Arabic and English digits-in-noise tests: Effects of test language and at-home testing [PDF]
PurposeThe digits-in-noise (DIN) test is used widely in research and, increasingly, remote hearing screening. The reported study aimed to provide basic evaluation data for browser-based DIN software, which allows remote testing without installation of an
Stone, Michael; id_orcid +7 more
core +2 more sources
Frontiers in Insect ScienceIntroductionSpatial repellents (also called spatial emanators) are widely marketed for personal protection against mosquito bites, yet their real‑world performance varies substantially and is rarely evaluated under standardized field conditions.
Edita E. Revay +19 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Thermal and mechanical nociceptive threshold testing in pregnant sheep [PDF]
, 2014 Objective: Analgesic regimes were compared in pregnant ewes after laparotomy by measuring thermal (TT) and mechanical (MT) nociceptive thresholds. Study design: Prospective randomised experimental study.
Murdoch, F.R. +10 more
core +1 more source
, 2022 Comparison of clinical sensitivity between Rapid antigen tests for SARS-CoV-2 to determine whether the sensitivity of different antigen tests differs significantly. Anatomical test location: ”N” anterior nasal cavity test, ”OP” deep oropharyngeal test,
Uffe Vest Schneider (12632548)
core +1 more source