Results 41 to 50 of about 9,482,745 (250)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Total domination versus paired domination [PDF]

, 2011
A dominating set of a graph G is a vertex subset that any vertex of G either belongs to or is adjacent to. A total dominating set is a dominating set whose induced subgraph does not contain isolated vertices.
Schaudt, Oliver
core   +4 more sources

Graphs with maximum size and given paired-domination number

Discrete Applied Mathematics, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Michael A. Henning, John McCoy, Justin Southey   +2 more
openaire   +1 more source

On Paired Double Domination for Degree Splitting Graphs of Some Graphs [PDF]

, 2023
In this paper, we introduced the new concept Paired double domination number for degree splitting graph of standard graphs. A paired – double dominating set of a graph G with no isolated vertex is a double dominating sets of vertices whose induced ...
V. Anusuya, M.N. Sree Valli
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Paired Disjunctive Domination Number of Middle Graphs

Fundamenta Informaticae
The concept of domination in graphs plays a central role in understanding structural properties and applications in network theory. In this study, we focus on the paired disjunctive domination number in the context of middle graphs, a transformation that captures both adjacency and incidence relations of the original graph.
Hande Tuncel Golpek, Zeliha Kartal Yildiz, Aysun Aytaç   +2 more
openaire   +2 more sources