Results 61 to 70 of about 9,014,600 (248)
On graphs for which the connected domination number is at most the total domination number [PDF]
, 2012 In this note, we give a finite forbidden subgraph characterization of the connected graphs for which any non-trivial connected induced subgraph has the property that the connected domination number is at most the total domination number. This question is
Schaudt, Oliver
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Paired-Domination in Grid Graphs.
, 2001 Every graph G = (V, E) has a dominating set S ⊆ V(G) such that any vertex not in S is adjacent to a vertex in S. We define a paired-dominating set S to be a dominating set S = {v1, v2,..., v2t-1, v2t} where M = {v1v2, v3v4, ..., v2t-1v2t} is a perfect ...
Proffitt, Kenneth Eugene
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
On the Roman Edge Domination Number of a Graph [PDF]
, 2010 Let G be a simple graph with vertex set V (G) and edge set E(G)
K. Ebadi +5 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 1998 In a graph G = (V, E) if we think of each vertex s as the possible location for a guard capable of protecting each vertex in its closed neighborhood N[s], then domination requires every vertex to be protected.
Haynes, Teresa W., Slater, Peter J.
core +1 more source
Bounding the paired-domination number of a tree in terms of its annihilation number
Filomat, 2014 A paired-dominating set of a graph G=(V, E) with no isolated vertex is a dominating set of vertices whose induced subgraph has a perfect matching. The paired-domination number of G, denoted by ?pr(G), is the minimum cardinality of a paired-dominating set of G.
Nasrin Dehgardi +2 more
openaire +2 more sources