Results 201 to 210 of about 80,959 (317)

Detecting foldback artifacts in long-reads. [PDF]

BMC Genomics
Heinz JM, Meyerson M, Li H.
europepmc   +1 more source

RNA‐Based Therapies for Inherited Metabolic Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri, Sonam Gurung, Roopkatha Ghosh, Philippa B. Mills, Julien Baruteau, Haiyan Zhou   +5 more
wiley   +1 more source

DNA-bound structure of Clostridioides difficile heme-sensing HsmR gives insight on how the unique dimer mode governs DNA specificity in MarR transcriptional regulators. [PDF]

Nucleic Acids Res
Rho S, Kwon N, Park S.
europepmc   +1 more source

CRISPR‐induced knockouts reveal a dual role for the soybean NFR5α gene in symbiotic nitrogen fixation and root hair development

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Nitrogen fixation in soybeans, facilitated by symbiotic interactions with rhizobia, is a cornerstone of sustainable agriculture, reducing reliance on synthetic fertilizers. However, the efficiency of symbiotic nitrogen fixation (SNF) varies due to natural genetic variation in SNF‐related genes.
Mohsen Niazian, Maxime de Ronne, Chantal J. Beauchamp, François Belzile, Davoud Torkamaneh   +4 more
wiley   +1 more source

Non-steroidal anti-inflammatory drugs conjugated to a synthetic peptide exhibit <i>in vitro</i> cytotoxic activity against cervical cancer and melanoma cells. [PDF]

RSC Med Chem
Castellar-Almonacid DA, Barragán-Cárdenas AC, Rodríguez-Mejia KG, Maldonado-Sanabria LA, Ardila-Chantré N, Mendoza-Mendoza JD, Parra-Giraldo CM, Rivera-Monroy JE, Rivera-Monroy ZJ, García-Castañeda JE, Fierro-Medina R.   +10 more
europepmc   +1 more source

siml, a new restriction endonuclease that recgnizes non-palindromic sequence 5′-GGGTC-3′(−3/0) [PDF]

, 1995
М. А. Абдурашитов, O. A. Belichenko, А. В. Шевченко, S. Kh. Degtyarev   +3 more
openalex   +1 more source

Potato dihaploids uncover diverse alleles to facilitate diploid potato breeding

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Commercial potato (Solanum tuberosum) in North America is a clonal autotetraploid crop, which complicates breeding. Efforts are underway to convert potato to a diploid inbred‐hybrid crop, allowing breeders to more quickly meet market and environmental demands.
Sapphire Coronejo, Brieanne Vaillancourt, John P. Hamilton, Xiaoxi Meng, Kathrine Mailloux, Grace Christensen, Jessica Huege, Kathleen M. Shaw, Husain I. Agha, Oluwafemi Alaba, Kristen Brown‐Donovan, James S. Busse, Andy Hamernik, Maria V. Caraza‐Harter, Lucas Heroux, Hemant Balasaheb Kardile, Ericka Knoeck, Peyton L. Sorensen, Diana Spencer, Solomon Yilma, Paul C. Bethke, David Douches, Joshua Parsons, Vidyasagar Sathuvalli, Ek Han Tan, Jeffrey B. Endelman, C. Robin Buell, Laura M. Shannon   +27 more
wiley   +1 more source

Complete chloroplast genome sequence of Silene jenisseensis, Arenaria juncea, and Gypsophila licentiana: gene organization, comparative analysis, and phylogenetic relationships. [PDF]

BMC Genomics
Cui T, Lian C, Ma R, Yang H, Gao Z, Chen S, Yang J.   +6 more
europepmc   +1 more source

Molecular polymorphisms that underlie trait variation in crops: Lessons learned from soybean

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Genetic variation within a germplasm is important in crop improvement, providing a foundation for breeders to develop new varieties. Traits of agronomic and economic importance are often mapped to identify the genetic basis of observed phenotypes, oftentimes using quantitative trait locus (QTL) analysis.
Mary Jane C. Espina, Aaron J. Lorenz, Robert M. Stupar   +2 more
wiley   +1 more source

Mechanistic study of <i>TFE3</i> breakage in <i>TFE3</i>-rearranged renal cell carcinoma: the perspective of non-canonical DNA structures and their stability. [PDF]

Front Genet
Zhang X, Dang Q, Pan X, Deng Z, Xu Y, Gan W, Guo H.   +6 more
europepmc   +1 more source