A guide to characterizing the dynamic mitochondria–endoplasmic reticulum contact sites
The FEBS Journal, EarlyView.The dynamism, heterogeneity, and functional complexity of mitochondria–endoplasmic reticulum contacts (MERCs) require combined methodological approaches to offset limitations of individual techniques. Here, we review available tools and methodologies for MERC research, outline key technical challenges, and discuss how recent advances deliver ...
Antigoni Diokmetzidou, Luca Scorrano
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Unraveling the mitochondrial genome of <i>Quercus litseoides</i>: a step towards conservation of an endangered species. [PDF]
Front Plant SciShen RH +7 more
europepmc +1 more source
The FEBS Journal, EarlyView.We investigated the role of the signal regulatory protein alpha (SIRPα)/CD47 axis in phagocytosis by disrupting the SIRPA gene in the THP‐1 cell line. The SIRPα KO THP‐1 cells retained their monocyte and macrophage characteristics similar to their wild‐type (WT) counterparts.
Saitong Muneekaew +5 more
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Analysis of the spacing between the two palindromes of activation sequence-1 with respect to binding to different TGA factors and transcriptional activation potential [PDF]
, 2002 Stefanie Krawczyk
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The FEBS Journal, EarlyView.A genome‐wide CRISPR‐Cas9 screen identified H3K27 methylation as a key regulator of T‐cell lymphoma sensitivity to dimethyl fumarate (DMF). Specifically, inhibition of enhancer of zeste homolog 2 (EZH2) enhanced DMF‐induced cell death in malignant T cells. These results provide functional evidence for the role of EZH2 in modulating drug sensitivity and
Jan P. Teubner +17 more
wiley +1 more source
Complete mitochondrial genome of Polygonatum cyrtonema Hua reveals variation diversity and evolutionary trends. [PDF]
BMC Plant BiolLuo H, Ren F, Cao G, Wang D, Jia Q.
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Formation of Large Palindromic DNA by Homologous Recombination of Short Inverted Repeat Sequences in Saccharomyces cerevisiae [PDF]
, 2002 David K. Butler +2 more
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The FEBS Journal, EarlyView.KDM4A, a chromatin eraser, localizes to the centrosomes. Its demethylase activity is essential for maintaining centrosome number and integrity, independent of gene expression changes. Loss of KDM4A leads to centrosome amplification, pseudo‐bipolar spindle formation, and chromosome segregation errors, including micronuclei and chromatin bridges.
Pratim Chowdhury +16 more
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High nucleotide skew palindromic DNA sequences function as replication origins due to their unzipping propensity [PDF]
Parthasarathi Sahu +3 more
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A Novel IS Element, IS 621 , of the IS 110 /IS 492 Family Transposes to a Specific Site in Repetitive Extragenic Palindromic Sequences in Escherichia coli [PDF]
, 2003 Sunju Choi, Shinya Ohta, Eiichi Ohtsubo
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