Results 51 to 60 of about 426,395 (339)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Measuring palliative care integration in Malawi through service provision, access, and training indicators: the Waterloo Coalition Initiative

BMC Palliative Care
Background Fewer than 1 in 20 people on the African continent in need of palliative care receive it. Malawi is a low-income country in sub-Saharan Africa that has yet to achieve advanced palliative care integration accompanied by unrestricted access to ...
Fatia Kiyange, Mackuline Atieno, Emmanuel B. K. Luyirika, Zipporah Ali, Helena Musau, Lameck Thambo, John Y. Rhee, Eve Namisango, William E. Rosa   +8 more
doaj   +1 more source

Health care professionals' perceptions towards lifelong learning in palliative care for general practitioners: a focus group study [PDF]

, 2014
Background: There is a growing need for palliative care. The majority of palliative patients prefer their general practitioner (GP) to organize their palliative home care. General practitioners need a range of competences to perform this task.
Deveugele, Myriam, Pype, Peter, Stes, Ann, Symons, Linda, Van den Eynden, Bart, Wens, Johan   +5 more
core   +2 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Ethnicity, Older People and Palliative Care [PDF]

, 2012
This report brings together established and developing work on older people, ethnicity and palliative care from PRIAE (Policy Research Institute on Ageing and Ethnicity) and the National Council for Palliative Care (NCPC).

core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Prognostic awareness and its association with health outcomes in the last year of life

Cancer Medicine, 2023
Background Little research has examined changes in prognostic awareness (PA) in the last year of life and the extent PA change was associated with anxiety, depression, and spiritual well‐being among metastatic cancer patients.
Semra Ozdemir, Isha Chaudhry, Sean Ng, Irene Teo, Chetna Malhotra, Eric Andrew Finkelstein, COMPASS Study Group   +6 more
doaj   +1 more source

Funding models in palliative care: lessons from international experience [PDF]

, 2017
Background:Funding models influence provision and development of palliative care services. As palliative care integrates into mainstream health care provision, opportunities to develop funding mechanisms arise.
Allan, Simon, Bausewein, Claudia, Cassel, J Brian, Cassel, J. Brian, Csikos, Agnes, Csikós, Ágnes, Eychmueller, Steffen, Furst, Carl Johan, Fürst, Carl Johan, García-Baquero Merino, Teresa, Groeneveld, E Iris, Groeneveld, E. Iris, Hasselaar, Jeroen, Haugen, Dagny Faksvag, Haugen, Dagny Faksvåg, Keller, Heike Gudat, Krajnik, Malgorzata, Merino, Teresa Garcia-Baquero, Merino, Teresa García Baquero, Murtagh, Fliss E. M., Murtagh, Fliss E.M., Murtagh, Fliss EM, Piper, Kym, Ryan, Karen, Swetenham, Kate, Swetenhaml, Kate   +25 more
core   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Nursing informatics competency and its associated factors among palliative care nurses: an online survey in mainland China

BMC Nursing
Background Nursing informatics (NI) competency is a required core competency for high-quality care in digitally enabled healthcare environments. Given the increasing reliance on digital health in palliative care settings, it becomes crucial to evaluate ...
Junchen Guo, Junqingzhao Liu, Chaoyi Liu, Ying Wang, Xianghua Xu, Yongyi Chen   +5 more
doaj   +1 more source