Results 51 to 60 of about 445,085 (360)

Palliative care for people with non-malignant lung disease: summary of current evidence and future direction [PDF]

, 2013
Background: The physical and psychosocial needs of patients with chronic non-malignant lung disease are comparable to those with lung cancer. This article will focus on chronic obstructive pulmonary disease, interstitial lung disease and cystic fibrosis ...
Boland, Jason, Martin, Jonathan, Ross, Joy R, Ross, Joy R., Wells, Athol U, Wells, Athol U.   +5 more
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Nursing informatics competency and its associated factors among palliative care nurses: an online survey in mainland China

BMC Nursing
Background Nursing informatics (NI) competency is a required core competency for high-quality care in digitally enabled healthcare environments. Given the increasing reliance on digital health in palliative care settings, it becomes crucial to evaluate ...
Junchen Guo, Junqingzhao Liu, Chaoyi Liu, Ying Wang, Xianghua Xu, Yongyi Chen   +5 more
doaj   +1 more source

“From good hearted community members we get volunteers” – an exploratory study of palliative care volunteers across Africa

BMC Palliative Care, 2020
Background Volunteers play a significant role in supporting hospice and palliative care in Africa, but little is known about the types of volunteers, their motivations and roles in service delivery.
Carolin Clara Loth, Eve Namisango, Richard Antony Powell, Katharina Henny Pabst, Mhoira Leng, Mohamed Hamada, Lukas Radbruch   +6 more
doaj   +1 more source

Development of a patient-reported palliative care-specific health classification system: the POS-E [PDF]

, 2017
BackgroundGeneric preference-based measures are commonly used to estimate quality-adjusted life-years (QALYs) to inform resource-allocation decisions.
Dzingina, Mendwas, Higginson, Irene J., McCrone, Paul, Murtagh, Fliss, Murtagh, Fliss E. M., Murtagh, Fliss E.M.   +5 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Conceptualising effective symptom management in palliative care: a novel model derived from qualitative data

BMC Palliative Care, 2022
Background Pain, breathlessness and fatigue are some of the most challenging symptoms to manage in patients with advanced disease. Specialist palliative care leads to better symptom management, but factors contributing to successful symptom management in
Emma J. Chapman, Simon Pini, Zoe Edwards, Yousuf Elmokhallalati, Fliss E. M. Murtagh, Michael I. Bennett   +5 more
doaj   +1 more source

Access to Specialist Palliative Care Services and Place of Death in Ireland [PDF]

, 2013
The aim of this report is to provide data, analysis and commentary to stimulate discussion on emerging trends in relation to the provision of specialist palliative care in Ireland.
Eugene Murray, Kathleen McLoughlin, Sharon Foley   +2 more
core  

Early identification of and proactive palliative care for patients in general practice, incentive and methods of a randomized controlled trial [PDF]

, 2016
BACKGROUND According to the Word Health Organization, patients who can benefit from palliative care should be identified earlier to enable proactive palliative care.
Engels, Yvonne, Galesloot, Cilia, Groot, Marieke, Prins, Judith, Thoonsen, Bregje, van Weel, Chris, Verhagen, Stans, Vissers, Kris   +7 more
core   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source