Palmitic acid: Enabling the tumor’s nerves
Cell Metabolism, 2022 Diet can influence tumor aggressiveness. Recently in Nature, a study by Pascual et al. provided evidence that dietary palmitic acid induces an epigenetic memory by modulating particular histone methylation marks in cancer cells. This allows cancer cells to activate extracellular matrix secretion from Schwann cells of the tumor microenvironment, which ...
Alkan, H. Furkan +2 more
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Impact of Dietary Palmitic Acid on Lipid Metabolism
Frontiers in Nutrition, 2022 Palmitic acid (PA) is ubiquitously present in dietary fat guaranteeing an average intake of about 20 g/d. The relative high requirement and relative content in the human body, which accounts for 20–30% of total fatty acids (FAs), is justified by its relevant nutritional role.
Murru E., Manca C., Carta G., Banni S.
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Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12 [PDF]
Journal of Biomedical Science, 2014 Excessive saturated fatty acids have been considered to be one of major contributing factors for the dysfunction of skeletal muscle cells as well as pancreatic beta cells, leading to the pathogenesis of type 2 diabetes.PA induced cell death in a dose dependent manner up to 1.5 mM, but AA protected substantially lipotoxicity caused by PA at even low ...
Hyae Gyeong Cheon, Young Sik Cho
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Activation of Palmitic Acid by Human Spermatozoa [PDF]
Journal of Andrology, 1985 Human spermatozoa were studied to determine if a long chain fatty acid, CoASH ligase (AMP) (E.C. 6.2.1.3), was present. Ligase activity was measured with a radioligand millipore filter technique and was readily detectable in spermatozoa or in the protein fraction extracted with Triton X‐100, but was not present in seminal plasma.
Robert E. Jones +2 more
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Calcium palmitate and -palmitic acid in gallstones [PDF]
Gut, 1970 Calcium palmitate occurred in 20% of the gallstones studied in this laboratory by x-ray diffraction and was the most important crystalline constituent after the different forms of cholesterol and calcium carbonate. Only one calculus contained alpha-palmitic acid.
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Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids and its modification by Stearoyl-CoA desaturases and cyclic AMP [PDF]
, 2011 Podocyte apoptosis is a hallmark in the development and progression of diabetic nephropathy (DN). Several factors of the diabetic milieu are known to induce podocyte apoptosis. Currently, the role of free fatty acids (FFAs) for podocytopathy and podocyte
Sieber, Jonas
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The difluoromethylene (CF2) group in aliphatic chains : synthesis and conformational preference of palmitic acids and nonadecane containing CF2 groups [PDF]
, 2014 Funding: ERC Advanced Investigator Grant (D.O'H).The syntheses of palmitic acids and a nonadecane are reported with CF2 groups located 1,3 or 1,4 to each other along the aliphatic chain. Specifically 8,8,10,10- and 8,8,11,11-tetrafluorohexadecanoic acids
Callejo, Ricardo +3 more
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Sustainable intensification? Increased production diminishes omega-3 content of sheep milk [PDF]
, 2020 Intensifying agricultural production alters food composition, but this is often ignored when assessing system sustainability, yet it could compromise consumers’ health and the concept of ‘sustainable diets’.
Atsali, I. +10 more
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Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated-skeletal muscle insulin resistance [PDF]
, 2014 Obesity and saturated fatty acid (SFA) treatment are both associated with skeletal muscle insulin resistance (IR) and increased macrophage infiltration. However, the relative effects of SFA and unsaturated fatty acid (UFA)-activated macrophages on muscle
Aguirre +67 more
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Fatty acid composition and technological quality of the lipids produced by the microalga Scenedesmus dimorphus 1237 as a function of culturing conditions [PDF]
, 2016 Scendesmus dimorphus is an oleaginous eukaryotic microalga, able to produce and accumulate lipids up to a weight fraction of 49%. Aim of the present work is investigating the production of lipids by S.
Bravi, Marco, Cicci, Agnese
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