Results 191 to 200 of about 5,176,832 (349)

Stable Cholesterol-Palmitic Acid Sterosomes as Smart Nanocarriers for pH-Sensitive Doxorubicin Delivery in Breast Cancer Therapy. [PDF]

Pharmaceutics
Lee JM, Lee CS, Lee CY, Lee M, Hwang HS.
europepmc   +1 more source

Development of NAFLD‐Specific Human Liver Organoid Models on a Microengineered Array Chip for Semaglutide Efficacy Evaluation

Cell Proliferation, EarlyView.
Microporous array organ chips were integrated with commercially available well plates to develop organoid chip platforms, which enable modelling of hepatic physiology and non‐alcoholic fatty liver disease (NAFLD) pathogenesis, as well as evaluation of semaglutide therapeutics. ABSTRACT Progressive non‐alcoholic fatty liver disease (NAFLD) may culminate
Xiao‐yan You, Xiang‐yang Li, Hui Wang, Guo‐ping Zhao   +3 more
wiley   +1 more source

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

Cell Proliferation, EarlyView.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo, Zexin Yang, Junsen She, Chen Fang, Yizhi Hu, Hefeng Huang, Ling Gao   +6 more
wiley   +1 more source

Zebrafish model of palmitic acid induced MAFLD recapitulates pathways conserved in mice and humans. [PDF]

Sci Rep
Bhattacharya D, Kaushal S, Chakraborty B, Raha A, Dutta T, Shekhar H, Koner AL, Kumar S, Ramachandran R, Kaur Dhanjal J, Minocha S.   +10 more
europepmc   +1 more source

Unveiling the Crucial Nexus: Mitochondrial Quality Control as a Central Driver in Metabolic Dysfunction‐Associated Steatotic Liver Disease Pathogenesis

Cell Proliferation, EarlyView.
Mitochondrial quality control (MQC) impairment plays a central role in driving the pathogenesis of metabolism‐associated steatotic liver disease (MASLD). Specifically, this is manifested as reduced mitophagy; increased mitochondrial fission and decreased fusion; and impaired mitochondrial biogenesis.
Wenkai Fu, Junqi Wang, Nan Lu, Zhijiang Guo, Sang‐Bing Ong, Yong Gao, Hao Zhou, Xing Chang, Miao Meng   +8 more
wiley   +1 more source

Optimized Preparation of Decanoic-palmitic Acid/SiO_2 Composite Phase Change Materials Based on Uniform Design

, 2015
Shang Jian-l
openalex   +1 more source

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

Palmitic Acid Induces Ferroptosis in Retinal Microvascular Endothelial Cells by Palmitoylation of Keap1 to Affect Diabetic Retinopathy. [PDF]

Invest Ophthalmol Vis Sci
Mao Z, Yang W, Chao Y, Chen Z, Zou Y.
europepmc   +1 more source

Acidolysis of terebinth fruit oil with palmitic and caprylic acids in a recirculating packed bed reactor: optimization using response surface methodology

, 2016
Derya Koçak Yanık, Hasene Keskin Çavdar, Sibel Fadı́loğlu, Fahrettin Göğüş   +3 more
openalex   +2 more sources

Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes [PDF]

, 2009
Matteo Ricchi, Maria Rosaria Odoardi, Lucia Carulli, Claudia Anzivino, Stefano Ballestri, Adriano Pinetti, Luca Fantoni, Fabio Marra, Marco Bertolotti, Sebastiano Banni, Amedeo Lonardo, Nicola Carulli, Paola Loria   +12 more
openalex   +1 more source