Results 141 to 150 of about 92,966 (245)

Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation

open access: yesBiological Reviews, EarlyView.
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Victor Murison   +3 more
wiley   +1 more source

Large‐Scale Production of Expandable Hepatoblast Organoids and Polarised Hepatocyte Organoids From hESCs Under 3D Static and Dynamic Suspension Conditions

open access: yesCell Proliferation, EarlyView.
Under 3D suspension culture condition, the expandable hepatoblast organoids and mature polarised hepatocyte organoids were established by low concentration of Matrigel from human embryonic stem cells, which recapitulated the gene expression signatures and functions of primary human hepatoblast and hepatocytes.
Haibin Wu   +14 more
wiley   +1 more source

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

open access: yesCell Proliferation, EarlyView.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye   +6 more
wiley   +1 more source

Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging

open access: yesCell Proliferation, EarlyView.
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi   +6 more
wiley   +1 more source

Targeting FABP4 to Inhibit AGEs‐RAGE/NF‐κB Signalling Effectively Ameliorates Nucleus Pulposus Dysfunction and Angiogenesis in Obesity‐Related Intervertebral Disc Degeneration

open access: yesCell Proliferation, EarlyView.
Obesity promotes the progression of intervertebral disc degeneration (IVDD) through the mTORC1/FABP4 axis. Targeting FABP4 effectively ameliorates nucleus pulposus dysfunction and angiogenesis in obesity‐related IVDD. ABSTRACT Intervertebral disc degeneration (IVDD) is a primary contributor to low back pain, posing significant social and economic ...
Lin Han   +8 more
wiley   +1 more source

Analyzing free fatty acids in seminal plasma from asthenozoospermia patients undergoing antioxidant therapy. [PDF]

open access: yesJBRA Assist Reprod
Amirjannati N   +7 more
europepmc   +1 more source

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