Results 151 to 160 of about 39,498 (303)

Data from Loss of Optineurin Drives Cancer Immune Evasion via Palmitoylation-Dependent IFNGR1 Lysosomal Sorting and Degradation

, 2023
Wan Du, Fang Hua, Xiong Li, Jian Zhang, Shasha Li, Weichao Wang, Jiajia Zhou, Weimin Wang, Peng Liao, Yijian Yan, Gaopeng Li, Shuang Wei, Sara Grove, Linda Vatan, Witold Zgodziński, Marek Majewski, Grzegorz Wallner, Haoyan Chen, Ilona Kryczek, Jing‐Yuan Fang, Weiping Zou   +20 more
openalex   +1 more source

CLDN6 inhibits breast cancer growth and metastasis through SREBP1-mediated RAS palmitoylation

Cellular & Molecular Biology Letters
Breast cancer (BC) ranks as the third most fatal malignant tumor worldwide, with a strong reliance on fatty acid metabolism. CLDN6, a candidate BC suppressor gene, was previously identified as a regulator of fatty acid biosynthesis; however, the ...
Q. Jin, Da Qi, Mingzi Zhang, Huinan Qu, Yuan Dong, Minghao Sun, Chengshi Quan   +6 more
semanticscholar   +1 more source

T‐cell exhaustion from a multiomics perspective: Differentiation mechanisms and regulatory networks in the journey from progenitor‐Exhausted T cells to terminally exhausted T cells

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
(1) Core Process: Persistent antigen, from TDLNs to TME, drives Tpex → Tex‐int → Tex‐term differentiation. (2) Multiomics Regulation: This fate transition is orchestrated by a co‐ordinated, multi‐layered molecular network. (3) Functional Outcome: Dysregulated signalling and surging co‐inhibitory receptors lock in proliferative arrest and functional ...
Tong Zhu, Xiaoyu Teng, Qinlian Jiao, Yidan Ren, Yunshan Wang, Maoxiao Feng   +5 more
wiley   +1 more source

Palmitoylation of caspase-6 by HIP14 regulates its activation [PDF]

, 2016
Niels H. Skotte, Shaun S. Sanders, Roshni R. Singaraja, Dagmar E. Ehrnhoefer, Kuljeet Vaid, Xiaofan Qiu, Srinivasaragavan Kannan, Chandra Verma, Michael R. Hayden   +8 more
openalex   +1 more source

AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca2+-Permeable AMPA Receptors to Control LTP

Cell Reports, 2018
Summary: Ca2+-permeable AMPA-type glutamate receptors (CP-AMPARs) containing GluA1 but lacking GluA2 subunits contribute to multiple forms of synaptic plasticity, including long-term potentiation (LTP), but mechanisms regulating CP-AMPARs are poorly ...
Alicia M. Purkey, Kevin M. Woolfrey, Kevin C. Crosby, Dominik G. Stich, Wallace S. Chick, Jason Aoto, Mark L. Dell’Acqua   +6 more
doaj   +1 more source

Simvastatin modulates estrogen signaling in uterine leiomyoma via regulating receptor palmitoylation, trafficking and degradation

, 2021
Sadia Afrin, Malak El Sabeh, Md Soriful Islam, Mariko Miyashita‐Ishiwata, Minnie Malik, William H. Catherino, Askar M. Akimzhanov, Darren Boehning, Qiwei Yang, Ayman Al‐Hendy, James H. Segars, Mostafa A. Borahay   +11 more
openalex   +2 more sources

Palmitoylation of Platelet Proteins

Platelets, 1994
Palmitoylation as incorporation of [(3)H] palmitic acid into proteins occurred in platelets as in other cell systems. The linkage of palmitic acid to platelet proteins was stable to SDS and organic solvents but was sensitive to hydroxylamine, consistent with oxyester or thioester bond(s). Non-reduced SDS PAGE analysis revealed that the most prominantly
openaire   +2 more sources

Protein S-palmitoylation in cellular differentiation [PDF]

, 2017
Mingzi M. Zhang, Howard C. Hang
openalex   +1 more source

Advances in understanding palmitoylation in female reproductive disorders: Mechanisms and future directions

Medicine Plus
Protein palmitoylation modification is a key lipidated post-translational modification that dynamically regulates protein function, subcellular localization, and signaling pathways in eukaryotic cells, with important implications for the onset and ...
Zhenteng Liu, Feng Deng, Zelin Zhang, Hongchu Bao, Ping Zhou, Rong Li   +5 more
doaj   +1 more source

Protein Modification: Palmitoylation in G-protein signaling pathways [PDF]

, 1995
Elliott M. Ross
openalex   +1 more source