Results 251 to 260 of about 34,702 (278)
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Biochemical and Biophysical Research Communications, 1997
Tubulin is a very water soluble protein, yet a significant portion is firmly associated with cell membranes. Because recent work has shown that palmitoylation is a dynamic process that can alter the targeting of proteins to membranes, we tested whether or not tubulin could be palmitoylated to account for its membrane location.
A M, Zambito, J, Wolff
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Tubulin is a very water soluble protein, yet a significant portion is firmly associated with cell membranes. Because recent work has shown that palmitoylation is a dynamic process that can alter the targeting of proteins to membranes, we tested whether or not tubulin could be palmitoylated to account for its membrane location.
A M, Zambito, J, Wolff
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Palmitoylation and palmitoyl-transferases in Plasmodium parasites
Biochemical Society Transactions, 2015Protein post-translational modifications (PTM) are commonly used to regulate biological processes. Protein S-acylation is an enzymatically regulated reversible modification that has been shown to modulate protein localization, activity and membrane binding.
Nicola, Hodson +3 more
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Assays of protein palmitoylation
Methods, 2006Protein palmitoylation plays an important role in the structure and function of a wide array of proteins. Unlike other lipid modifications, protein palmitoylation is highly dynamic and cycles of palmitoylation and depalmitoylation can regulate protein function and localization.
Renaldo C, Drisdel +3 more
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Palmitoylation of serotonin receptors
Biochemical Society Transactions, 2013The covalent attachment of palmitic acid to one or more cysteine residues (S-palmitoylation) is a widespread modification of signalling proteins. With the finding that palmitoylation is a dynamic process, it is now widely accepted that repeated cycles of palmitoylation/depalmitoylation could be involved in the regulation of multiple signalling ...
Nataliya, Gorinski, Evgeni, Ponimaskin
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Science Signaling
Palmitoylation of intact or cleaved gasdermin D causes plasma membrane pore formation.
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Palmitoylation of intact or cleaved gasdermin D causes plasma membrane pore formation.
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Aberrant palmitoylation in Huntington disease
Biochemical Society Transactions, 2015Huntington disease (HD) is an adult-onset neurodegenerative disease caused by a CAG expansion in the HTT gene. HD is characterized by striatal atrophy and is associated with motor, cognitive and psychiatric deficits. In the presence of the HD mutation, the interactions between huntingtin (HTT) and huntingtin interacting protein 14 (HIP14 or DHHC17) and
Shaun S, Sanders, Michael R, Hayden
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Science Signaling, 2020
Interrupting the palmitoylation-depalmitoylation cycle of the transcriptional regulator STAT3 relieves IBD symptoms in mice.
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Interrupting the palmitoylation-depalmitoylation cycle of the transcriptional regulator STAT3 relieves IBD symptoms in mice.
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