Journal of Anaesthesiology Clinical Pharmacology, 2021 Background and Aims: Postanesthesia shivering (PAS) is a common, distressing experience. Ondansetron, the classical 5HT3 antagonist has been in use for its prevention since long.
Manoj K Sharma +2 more
doaj +1 more source
Palonosetron-5-HT3Receptor Interactions As Shown by a Binding Protein Cocrystal Structure. [PDF]
, 2016 Palonosetron is a potent 5-HT3receptor antagonist and an effective therapeutic agent against emesis. Here we identify the molecular determinants of compound recognition in the receptor binding site by obtaining a high resolution structure of palonosetron
Lillestol, Reidun K +3 more
core +1 more source
Acute emesis: moderately emetogenic chemotherapy [PDF]
, 2010 This paper is a review of the recommendations for the prophylaxis of acute emesis induced by moderately emetogenic chemotherapy as concluded at the third Perugia Consensus Conference, which took place in June 2009.
Bria, Emilio +6 more
core +1 more source
NEPA, a new fixed combination of netupitant and palonosetron, is a cost-effective intervention for the prevention of chemotherapy-induced nausea and vomiting in the UK [PDF]
, 2017 Background: The objective was to evaluate the cost-effectiveness of NEPA, an oral fixed combination netupitant (NETU, 300 mg) and palonosetron (PA, 0.5 mg) compared with aprepitant and palonosetron (APPA) or palonosetron (PA) alone, to prevent ...
Bourhis, Francois +7 more
core +2 more sources
Randomised Control Study of Palonosetron Versus Dexamethasone in Preventing Postoperative Nausea and Vomiting Following Ear and Nose Surgeries under General Anesthesia [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Postoperative Nausea and Vomiting (PONV) is defined as any nausea or vomiting that occurs during the first 48 hours after surgery. It is considered as a distressing event following anaesthesia.
Anju Annie Paul +6 more
doaj +1 more source
pharma-kritik, 2008 Wie zum Beispiel Ondansetron wirkt Palonosetron gegen Brechreiz und Erbrechen im Zusammenhang mit emetogener Chemotherapie.
openaire +1 more source
Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting [PDF]
, 2016 BACKGROUND We examined the efficacy of olanzapine for the prevention of nausea and vomiting in patients receiving highly emetogenic chemotherapy.
Bajaj, Madhuri +9 more
core +1 more source
Indian Journal of Anaesthesia, 2017 Background and Aims: Post-operative nausea and vomiting (PONV) is highly distressing and unpleasant symptom. Dexamethasone and palonosetron are effective antiemetics with minimal side effect profile.
Arindam Chatterjee +5 more
doaj +1 more source
Antiemetic research: future directions [PDF]
, 2010 PURPOSE AND METHODS: As a part of reviewing the Multinational Association of Supportive Care in Cancer (MASCC) antiemetic guidelines in Perugia in 2009, an expert group identified directions for future antiemetic research.
Aapro, Matti +5 more
core +1 more source
Palonosetron has superior prophylactic antiemetic efficacy compared with ondansetron or ramosetron in high-risk patients undergoing laparoscopic surgery: a prospective, randomized, double-blinded study [PDF]
Korean Journal of Anesthesiology, 2013 BackgroundPostoperative nausea and vomiting (PONV) continues to be a major problem, because PONV is associated with delayed recovery and prolonged hospital stay.
Sung-Hoon Kim +5 more
doaj +1 more source