Results 41 to 50 of about 2,968 (201)

Palonosetron: An Evidence-Based Choice in Prevention of Nausea and Vomiting Induced by Moderately Emetogenic Chemotherapy

, 2012
Aims and background In 2003, the second-generation, 5-HT3 receptor antagonist (5-HT3 RA) palonosetron was approved by the FDA for the prevention of nausea and vomiting associated with highly and moderately emetogenic chemotherapy. We reviewed the current
Isabella Testa, Francesco Agustoni, Luigi Celio, Filippo de Braud, Katia Dotti   +4 more
core   +2 more sources

A randomized study to compare palonosetron with ondansetron for prevention of postoperative nausea and vomiting following middle ear surgeries

Journal of Anaesthesiology Clinical Pharmacology, 2019
Background and Aims: Postoperative nausea and vomiting (PONV) has multifactorial etiology. It is a commonly encountered morbidity after anesthesia specially following middle ear surgery. Various antiemetic medications have been tried with mixed responses.
Shubhangi Sharma, Sangeeta Khanna, Jyotirmoy Das, Yatin Mehta, Kumud Kumar Handa   +4 more
doaj   +1 more source

An Intraoperative EEG Biomarker for Postoperative Delirium Predicting Based on Interpretable Deep Learning Framework

MedComm, Volume 7, Issue 9, September 2026.
An interpretable intraoperative EEG framework predicts postoperative delirium (POD) in older surgical patients. A data‐driven best temporal filter (BTF) reveals frontal sensitivity and captures a distinctive 2–12 Hz (δ–θ–α) spindle‐like target wave occurring more frequently in POD patients, enabling event‐quantifiable intraoperative monitoring and ...
Yinuo Zhang, Yan Zhu, Xinxin Zhang, Xinke Shen, Xuemiao Tang, Zhihong Lu, Chong Lei, Mengyu Li, Hailong Dong, Zhichao Liang, Quanying Liu, Guangchao Zhao   +11 more
wiley   +1 more source

Palonosetron auch bei verzögertem Erbrechen wirksam

, 2010
In den im Juni 2009 aktualisierten gemeinsamen MASCC/ESMO-Leitlinien wird jetzt erstmals der 5-HT3-Rezeptor-Antagonist Palonosetron gegenüber den anderen Vertre-tern dieser Substanzklasse bei der moderat emetogenen Chemotherapie favorisiert.
Karl B. Filip
core   +1 more source

A Scoping Review of 5‐HT3 Antagonist Antiemetic Medication Safety in the Management of Nausea and Vomiting of Pregnancy

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.
ABSTRACT Purpose The prescribing of 5‐hydroxytryptamine 3 receptor and type 3 serotonin receptor (5‐HT3) antagonists, particularly ondansetron, for nausea and vomiting in pregnancy (NVP) has increased globally. However, evidence on the safety of these medications in pregnancy remains unclear.
Shannon Morgan, Ebony Quintrell, Danielle J. Russell, Amina Rhaman, Aster Gebremedhin, Caitlin S. Wyrwoll, Erin Kelty   +6 more
wiley   +1 more source

Palonosetron compared with ondansetron in pediatric cancer patients: multicycle analysis of a randomized Phase III study [PDF]

, 2017
Aim: To investigate across multiple cycles the efficacy and safety of palonosetron in the prevention of chemotherapy-induced nausea and vomiting in pediatric cancer patients receiving highly or moderately emetogenic chemotherapy (HEC/MEC).
Basharova E, Nicolas P, Edita Kabickova, Kovács, Gábor, Gábor Kovács, Wachtel A, Tulla Spinelli, Spinelli T, Kabickova E, Antonio Wachtel, Elena Basharova, Pierre Nicolas   +11 more
core   +1 more source

A randomized, double-blind study to evaluate the efficacy of ramosetron and palonosetron for prevention of postoperative nausea and vomiting after gynecological laparoscopic surgery [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundPostoperative nausea and vomiting (PONV) is a common complication after anesthesia and surgery; 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists have been considered as a first-line therapy.
Soo Kyoung Park, Eun Jung Cho, Sung Hee Kang, Young Jun Lee, Dal-Ah Kim   +4 more
doaj   +1 more source

Comparative Study Between Fosaprepitant and Palonosetron in the Prophylaxis of Postoperative Nausea and Vomiting in Women Undergoing Laparoscopic Cholecystectomy: Prospective, Randomized and Double-Blind Study

Frontiers in Pharmacology, 2022
Objective: To test the hypothesis that the single use of fosaprepitant is not inferior to the use of palonosetron as antiemetic prophylaxis in the first 48 h after surgery in women undergoing laparoscopic cholecystectomy.Method: Eighty-eight nonsmoking ...
Estêvão Luiz Carvalho Braga, Nubia Verçosa, Ismar Lima Cavalcanti   +2 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Transient Postoperative Diabetes Insipidus With Hypovolemic Shock Temporally Associated With Dexmedetomidine, Propofol, and Sevoflurane: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Dexmedetomidine, propofol, and sevoflurane are widely used anesthetic agents, but reports of water metabolism disturbances—particularly drug‐induced diabetes insipidus (DI)—associated with their use remain extremely rare. We report a case of a 51‐year‐old Chinese man who developed abrupt high‐volume polyuria (> 600 mL/h; 24‐h output of 8750 mL)
Yuan Meng, Xiaoxiao Qu, Yue Jin, Chengwei Yin, Geping Zhang, Fang Xie, Rong Shi   +6 more
wiley   +1 more source